ArticleWorld journal of surgery2020
Perioperative Management and Outcomes of Hyperthyroid Patients Unable to Tolerate Antithyroid Drugs.
Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety of surgery for managing hyperthyroidism in patients with or without preoperative euthyroidism: A systematic review and meta-analysis.Endocrine · 2025Pooled it
- Article
- Early postoperative levothyroxine initiation after total thyroidectomy for Graves' disease.Endocrine journal · 2025Article
- Comparison of short-term outcomes following minimally invasive (endoscopic/robotic) vs open thyroidectomy for patients with thyroid cancer.European thyroid journal · 2025Article
- Preoperative Preparation in Hyperthyroidism and Surgery in the Hyperthyroid State.Sisli Etfal Hastanesi tip bulteni · 2024Review
- Outcomes and Predictors of 30-Day Readmissions for Hyperthyroidism: A Nationwide Study.Endocrinology and metabolism (Seoul, Korea) · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrior to thyroidectomy for hyperthyroidism, it is recommended that patients are managed with antithyroid drugs (ATDs) and rendered euthyroid to decrease the risk of thyroid storm. However, not all patients tolerate ATD and the risk of thyroid storm during thyroidectomy in these patients is unclear. Therefore, the aim of this study was to compare the management and outcomes of hyperthyroid patients that were on ATDs prior to surgery to those who were not. STUDY
designA prospectively maintained, single-institution database was queried for all hyperthyroid patients who were initially treated with ATDs and underwent thyroidectomy from January 1, 2012, to June 18, 2018. Patients were divided into two groups: (1) those on ATDs at surgery (ATD group) and (2) those who could not tolerate and stopped ATDs prior to surgery (no-ATD group). Demographic and clinical data were collected. Primary outcomes were readmissions/emergency department visits and postoperative complications within 30 days of thyroidectomy.
resultsOf the 248 patients, 231 were in the ATD group and 17 (7%) were in the no-ATD group. There were no mortalities or thyroid storm events in either group. There was no difference in Clavien-Dindo Grade 2 or 3 complications between the two groups. There were no ED visits or 30-day readmissions in the no-ATD group compared to 17 (7%) events in the ATD group (p = 1.0).
conclusionWhile it is preferable to render patients euthyroid prior to thyroidectomy for hyperthyroidism, results of this study suggest that when patients cannot tolerate ATDs, it is possible to perform thyroidectomy without increased risk of thyroid storm or intra- and postoperative complications.
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