Evidence map›Paper›PMID 32572223›Full record

ArticleNature microbiology2020

Genome-wide associations of human gut microbiome variation and implications for causal inference analyses.

David A Hughes, Rodrigo Bacigalupe, Jun Wang, Malte C Rühlemann, Raul Y Tito, Gwen Falony, Marie Joossens, Sara Vieira-Silva, Liesbet Henckaerts, Leen Rymenans and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 4 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 4 syntheses or guidelines pooled it, 274 citations in OpenAlex.

  1. Pooled it
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  12. The gut as a central hub for multi-organ crosstalk in aging.Cellular and molecular life sciences : CMLS · 2026
    Review
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74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

David A Hughes *MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-9644-8998
Rodrigo Bacigalupe *Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Jun WangDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Malte C RühlemannInstitute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.ORCID http://orcid.org/0000-0002-0685-0052
Raul Y TitoDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Gwen FalonyDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-2450-0782
Marie JoossensDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-8410-5528
Sara Vieira-SilvaDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-4616-7602
Liesbet HenckaertsDepartment of Microbiology, Immunology and Transplantation, KU Leuven-University of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-2880-1400
Leen RymenansDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Chloë VerspechtDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Susan RingPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Andre FrankeInstitute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.ORCID http://orcid.org/0000-0003-1530-5811
Kaitlin H WadeMRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.
Nicholas J TimpsonMRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK. N.J.Timpson@bristol.ac.uk.ORCID http://orcid.org/0000-0002-7141-9189
Jeroen RaesDepartment of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be.ORCID http://orcid.org/0000-0002-1337-041X
Rega Institute for Medical Research · BEUniversity of Bristol · GBChristian-Albrechts-Universität zu Kiel · DEAt Bristol · GBChinese Academy of Social Sciences · CNKU Leuven · BE

Funding

SUBTHRESHOLD MUSCLE AFFERENT INPUT TO DORSAL HORNF06TW002012 · FIC · UNIVERSITY OF CALIFORNIA DAVIS · PI KAUFMAN, MARC PETER · 1995 to 1995
–
Cancer Research UK 19169Cancer Research UK C18281/A19169Department of Health BRC-1215-20011Medical Research Council MC_UU_00011/6Medical Research Council MC_UU_12013/3Wellcome Trust 202802Wellcome Trust 202802/Z/16/ZWellcome Trust 204813/Z/16/Z
6 · The paper itself

Abstract

Recent population-based

Indexed as

Genome-Wide Association StudyAnimalsBifidobacteriumFecesGastrointestinal MicrobiomeGenotypeHumansMiceMicrobiotaPhenotypePolymorphism, Single NucleotideQuantitative Trait LociRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID32572223
PMCPMC7610462
OpenAlexW3035975458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.