Evidence map›Paper›PMID 32572126›Full record

ArticleScientific reports2020

Association between Serum Uric Acid and Nonalcoholic Fatty Liver Disease in Nonobese Postmenopausal Women: A Cross-sectional Study.

Ting Bao, Zhiye Ying, Li Gong, Jing Du, Guiyi Ji, Zhengzheng Li, Wei Gao, Xianweng Jiang, Hanwei Yang, Yan Huang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ting BaoHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Zhiye YingWest China Biomedical Big Data Centre, West China Hospital, Sichuan University, Chengdu, China.
Li GongOutpatient department, West China Hospital, Sichuan University, Chengdu, China.
Jing DuHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Guiyi JiHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Zhengzheng LiHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Wei GaoHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Xianweng JiangHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Hanwei YangHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Yan HuangHealth Management Center, West China Hospital, Sichuan University, Chengdu, China.
Huairong TangHealth Management Center, West China Hospital, Sichuan University, Chengdu, China. 1651682099@qq.com.
Sichuan University · CNWest China Hospital of Sichuan University · CNWest China Medical Center of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine the association between serum uric acid (sUA) and nonalcoholic fatty liver disease (NAFLD) in nonobese postmenopausal women. A total of 4323 female individuals over 18 years of age participated in this cross-sectional study. The subjects were divided into four groups according to menopause status and body mass index. sUA quartiles in this female population were categorized as follows: Q1 ≤ 230 mmol/L, Q2: 231-270 mmol/L, Q3: 271-310 mmol/L and Q4: ≥ 311 mmol/L. The presence or absence of NAFLD was assessed by abdominal ultrasonography. The prevalence of NAFLD was 38.8% in the general population, and the average age was 46.5 ± 11.3 years. Among nonobese and obese subjects, the prevalence of NAFLD was lower in nonmenopausal subjects than in postmenopausal subjects (nonobese: 20.74% vs 45.26%, respectively, P < 0.0001; obese: 70.51% vs 84.35%, respectively, P < 0.0001). After adjusting for age, current smoking status, current alcohol drinking status, diabetes, hypertension disease and triglyceride, the ORs (95% CIs) for NAFLD among individuals in Q2-Q4 were 1.518 (1.062-2.169), 1.431 (1.010-2.027) and 2.054 (1.442-2.927), respectively, P value for trend <0.0001. Higher sUA levels can be used as a predictive biomarker for NAFLD in nonobese postmenopausal women.

Indexed as

AdultBiomarkersBody Mass IndexCase-Control StudiesCross-Sectional StudiesFemaleHumansMiddle AgedNon-alcoholic Fatty Liver DiseasePostmenopausePrevalenceRisk FactorsUltrasonographyUric AcidBiomarkersUric Acid

Identifiers

PMID32572126
PMCPMC7308322
OpenAlexW3036914264

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.