Evidence map›Paper›PMID 32572085›Full record

ArticleScientific reports2020

The early predictive value of routine laboratory tests on the severity of acute pancreatitis patients in pregnancy: a retrospective study.

Di Jin, Jixue Tan, Jingsun Jiang, Dana Philips, Ling Liu

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pancreatitis in Pregnancy-Comprehensive Review.International journal of environmental research and public health · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Di JinDepartment of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jixue TanQueen Mary School, Medical College of Nanchang University, Nanchang, 330031, China.
Jingsun JiangDepartment of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Dana PhilipsWest China School of Medicine, Sichuan University, Chengdu, 610041, China.
Ling LiuDepartment of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, China. liulinggi@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis in pregnancy (APIP) varies in severity from a self-limiting mild condition to a severe life-threatening condition, and its severity is significantly correlated with higher risks of maternal and foetal death. This study evaluated the early predictive value of routine laboratory tests on the severity of APIP patients. We enrolled 100 patients with APIP in West China Hospital. Initial routine laboratory tests, including the biochemistry and hematologic tests were collected within 48 hours after the onset of APIP. For predicting SAP in AP, LDH had the highest specificity of 0.879. RDW was a suitable predictive marker as it had the sensitivity of 0.882. Lower levels of triglycerides (<4.72 mmol/L) predicted mild AP of APIP, with an area under the curve (AUC) of 0.724, and a negative predictive value of 0.80. Furthermore, a risk score was calculated based on white blood cells, neutrophils, RDW, LMR and LDH, as an independent marker (adjusted odds ratio = 3.013, 95% CI 1.893 to 4.797, P < 0.001), with the highest AUC of 0.906, a sensitivity of 0.875 and a specificity of 0.828. In conclusion, the risk score we recommended was the powerful marker to aid in the early prediction of the severity of APIP patients.

Indexed as

Predictive Value of TestsAcute DiseaseAdultBiomarkersChinaClinical Laboratory TechniquesFemaleHumansLeukocyte CountNeutrophilsPancreatitisPregnancyPrognosisRetrospective StudiesROC CurveSensitivity and SpecificityBiomarkers

Identifiers

PMID32572085
PMCPMC7308294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.