Evidence map›Paper›PMID 32571989›Full record

ArticleInfection and immunity2020

A Small Membrane Stabilizing Protein Critical to the Pathogenicity of Staphylococcus aureus.

Seána Duggan, Maisem Laabei, Alaa Abdulaziz Alnahari, Eóin C O'Brien, Keenan A Lacey, Leann Bacon, Kate Heesom, Chih-Lung Fu, Michael Otto, Eric Skaar and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Formation of COBiofilm · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Extensive re-modelling of the cell wall during the development ofbioRxiv : the preprint server for biology · 2023
    Article
  9. The Old Yellow Enzyme OfrA FostersFrontiers in microbiology · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Seána Duggan *School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-6177-577X
Maisem Laabei *Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom.
Alaa Abdulaziz AlnahariSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Eóin C O'BrienHost-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
Keenan A LaceyHost-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
Leann BaconSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Kate HeesomUniversity of Bristol Proteomics Facility, Biomedical Sciences Building, Bristol, United Kingdom.
Chih-Lung FuPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, U.S. National Institutes of Health, Bethesda, Maryland, USA.
Michael OttoPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, U.S. National Institutes of Health, Bethesda, Maryland, USA.
Eric SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Rachel M McLoughlinHost-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
Ruth C MasseySchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom ruth.massey@bristol.ac.uk.ORCID 0000-0002-8154-4039
University of Bristol · GBTrinity College Dublin · IENational Institutes of Health · USUniversity of Bath · GBVanderbilt University Medical Center · US

Funding

Staphylococcal pathogenesisZIAAI000904 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI OTTO, MICHAEL · 2009 to 2025
$22.6M
Biotechnology and Biological Sciences Research CouncilWellcome TrustWellcome Trust 212258
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immune EvasionA549 Cellsalpha-DefensinsAnimalsBacteremiaBacterial ToxinsErythrocytesGene Expression ProfilingGene Expression RegulationHemeHemolysin ProteinsHomeostasisHumansIronMice, Inbred BALB CMice, Inbred C57BLalpha-DefensinsBacterial ToxinsHemeHemolysin Proteinshuman neutrophil peptide 1Ironstaphylococcal alpha-toxinStaphylococcal ToxoidVirulence Factorscytotoxinsimmune evasioniron homeostasisStaphylococcus aureusvirulence

Identifiers

PMID32571989
PMCPMC7440758
OpenAlexW3035299530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.