Evidence map›Paper›PMID 32571965›Full record

ArticleJournal of bacteriology2020

Structural Characterization of TssL from Acinetobacter baumannii: a Key Component of the Type VI Secretion System.

Federico M Ruiz, Juvenal Lopez, C Gastón Ferrara, Elena Santillana, Yanis R Espinosa, Mario F Feldman, Antonio Romero

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Structure and Function of the Dot/Icm T4SS.bioRxiv : the preprint server for biology · 2023
    Article
  4. Uncovering the Secretion Systems ofAntibiotics (Basel, Switzerland) · 2023
    Review
  5. Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-ResistantInternational journal of environmental research and public health · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Federico M RuizChemical and Physical Biology, Centro de Investigaciones Biológicas Margarita Salas, Madrid, Spain fruiz@cib.csic.es romero@cib.csic.es.ORCID 0000-0002-0385-7777
Juvenal LopezDepartment of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
C Gastón FerraraSchool of Engineering and Agronomy, National University Arturo Jauretche, Florencio Varela, Argentina.
Elena SantillanaChemical and Physical Biology, Centro de Investigaciones Biológicas Margarita Salas, Madrid, Spain.
Yanis R EspinosaGrupo de Bioquímica Teórica, Universidad Industrial de Santander, Bucaramanga, Colombia.
Mario F FeldmanDepartment of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Antonio RomeroChemical and Physical Biology, Centro de Investigaciones Biológicas Margarita Salas, Madrid, Spain fruiz@cib.csic.es romero@cib.csic.es.
Centro de Investigaciones Biológicas Margarita Salas · ESWashington University in St. Louis · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARIndustrial University of Santander · CO

Funding

INVESTIGATING TYPE VI SECRETION IN ACINETOBACTER BAUMANNII AND ITS INTERPLAY WITH ANTIBIOTIC RESISTAR01AI125363 · NIAID · WASHINGTON UNIVERSITY · PI FELDMAN, MARIO · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI125363
6 · The paper itself

Abstract

The type VI secretion system (T6SS) is a complex molecular nanomachine used by Gram-negative bacteria to deliver diverse effectors into adjacent cells. A membrane complex (MC) anchors this transport system to the bacterial cell wall. One of the proteins forming the MC is TssL, a cytoplasmic protein bound to the inner membrane through a single transmembrane helix. Here, we report the structure of the cytoplasmic N-terminal region of TssL from

Indexed as

Acinetobacter baumanniiBacterial ProteinsGene Expression Regulation, BacterialMolecular Dynamics SimulationMutationType VI Secretion SystemsBacterial ProteinsType VI Secretion SystemsAcinetobactersecretion systemsstructural biology

Identifiers

PMID32571965
PMCPMC7417833
OpenAlexW3036358830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.