Evidence map›Paper›PMID 32571874›Full record

ArticleThe Journal of biological chemistry2020

The bacterial copper resistance protein CopG contains a cysteine-bridged tetranuclear copper cluster.

Andrew C Hausrath, Nicholas A Ramirez, Alan T Ly, Megan M McEvoy

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Regulatory Characterization of Two Cop Systems for Copper Resistance inInternational journal of molecular sciences · 2025
    Article
  4. CopGBiology · 2024
    Article
  5. Article
  6. Article
  7. Veterinary record open · 2022
    Article
  8. Review
  9. Assessment ofFrontiers in microbiology · 2022
    Article
  10. Maturation ofFrontiers in microbiology · 2021
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew C HausrathInstitute for Society and Genetics, University of California, Los Angeles, California, USA.
Nicholas A RamirezMolecular Biology Institute, University of California, Los Angeles, California, USA.
Alan T LyInstitute for Society and Genetics, University of California, Los Angeles, California, USA.
Megan M McEvoyInstitute for Society and Genetics, University of California, Los Angeles, California, USA mcevoymm@ucla.edu.ORCID 0000-0002-4132-7355
University of California, Los Angeles · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss · 2010 to 2026
$21.4M
Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIST32AI007323 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peter John Bradley · 1988 to 2026
$8.6M
The Role of Protein Interactions in Microbial Copper/Silver ResistanceR01GM079192 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCEVOY, MEGAN M · 2007 to 2016
$2.4M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
NCRR NIH HHS S10 RR029205NIAID NIH HHS T32 AI007323NIDDK NIH HHS P30 DK089507NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R01 GM079192
6 · The paper itself

Abstract

CopG is an uncharacterized protein ubiquitous in Gram-negative bacteria whose gene frequently occurs in clusters of copper resistance genes and can be recognized by the presence of a conserved CxCC motif. To investigate its contribution to copper resistance, here we undertook a structural and biochemical characterization of the CopG protein from

Indexed as

Coatomer ProteinCopperCrystallography, X-RayCysteineGram-Negative BacteriaHumansOxidation-ReductionCoatomer ProteinCOPG1 protein, humanCopperCysteinecoppermetal homeostasismetal ion homeostasismetalloproteinmetal resistanceoxidation-reductionoxidation-reduction (redox)P. aeruginosaPseudomonas aeruginosastructure-functionthioredoxin

Identifiers

PMID32571874
PMCPMC7415965
OpenAlexW3036633493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.