ArticleBMJ open2020
Comparison of antibiotic prescribing records in two UK primary care electronic health record systems: cohort study using CPRD GOLD and CPRD Aurum databases.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Antibiotic use and survival from breast cancer: A population-based cohort study in England and Wales.Nature communications · 2025Article
- The burden of hand trauma surgery on primary care in the United Kingdom: a nation-wide analysis of antibiotic and opioid prescriptions.The Journal of hand surgery, European volume · 2025Article
- A systematic review on how primary care electronic medical record data have been used for antimicrobial stewardship.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Review
- Article
- Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study.Acta psychiatrica Scandinavica · 2023Article
- Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Incidence of acute otitis media from 2003 to 2019 in children ≤ 17 years in England.BMC public health · 2023Observational
- Incidence of pneumococcal disease from 2003 to 2019 in children ≤17 years in England.Pneumonia (Nathan Qld.) · 2023Article
- Comparison of Rheumatoid Arthritis Information Recorded in UK CPRD Aurum and CPRD GOLD Databases (Companion Paper 3).Clinical epidemiology · 2023Article
- Healthcare resource utilisation and cost of pneumococcal disease from 2003 to 2019 in children ≤17 years in England.PloS one · 2023Article
- Use of the CPRD Aurum Database: Insights Gained from New Data Quality Assessments.Clinical epidemiology · 2023Article
- Electronic Health Records and Antimicrobial Stewardship Research: a Narrative Review.Current epidemiology reports · 2022Review
- Incidence of nonvalvular atrial fibrillation and oral anticoagulant prescribing in England, 2009 to 2019: A cohort study.PLoS medicine · 2022Article
- Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD).BMJ quality & safety · 2022Article
- Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases.Clinical epidemiology · 2022Article
- Long term trends in natriuretic peptide testing for heart failure in UK primary care: a cohort study.European heart journal · 2021Article
- Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data.PloS one · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesWe aimed to evaluate recording of antibiotic prescribing from two primary care electronic health record systems.
designCohort study.
settingUK general practices contributing to the Clinical Practice Research Datalink (CPRD) databases: CPRD GOLD (Vision data) and CPRD Aurum (EMIS data). English CPRD GOLD general practices were analysed as a subgroup, as all CPRD Aurum practices were located in England.
participants158 305 patients were randomly sampled from CPRD Aurum and 160 394 from CPRD GOLD. OUTCOME MEASURES: Antibiotic prescriptions in 2017 were identified. Age-standardised and sex-standardised antibiotic prescribing rates per 1000 person years were calculated. Prescribing of individual antibiotic products and associated medical diagnoses was evaluated.
resultsThere were 101 360 antibiotic prescriptions at 883 CPRD Aurum practices and 112 931 prescriptions at 290 CPRD GOLD practices, including 112 general practices in England. The age-standardised and sex-standardised antibiotic prescribing rate in 2017 was 512.6 (95% CI 510.4 to 514.9) per 1000 person years in CPRD Aurum and 584.3 (582.1 to 586.5) per 1000 person years in CPRD GOLD (505.2 (501.6 to 508.9) per 1000 person years if restricted to practices in England). The 25 most frequently prescribed antibiotic products were similar in both databases. One or more medical codes were recorded on the same date as an antibiotic prescription for 72 989 (74%) prescriptions in CPRD Aurum, 84 756 (78%) in CPRD GOLD and 28 471 (78%) for CPRD GOLD in England. Skin, respiratory and genitourinary tract infections were recorded for 39 035 (40%) prescriptions in CPRD Aurum, 41 326 (38%) in CPRD GOLD, with 15 481 (42%) in English CPRD GOLD practices only.
conclusionEstimates for antibiotic prescribing and infection recording were broadly similar in both databases suggesting similar recording across EMIS and Vision systems. Future research on antimicrobial stewardship can also be conducted using primary care data in CPRD Aurum.
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