Evidence map›Paper›PMID 32571842›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

BCALM (AC099524.1) Is a Human B Lymphocyte-Specific Long Noncoding RNA That Modulates B Cell Receptor-Mediated Calcium Signaling.

Sarah C Pyfrom, Chaz C Quinn, Hannah K Dorando, Hong Luo, Jacqueline E Payton

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Single-nuclei transcriptome analysis of IgMFrontiers in immunology · 2025
    Article
  4. Review
  5. Article
  6. LNCing RNA to immunity.Trends in immunology · 2022
    Review
  7. Review
  8. Article
  9. Bioinformatic Tools for the Analysis and Prediction of ncRNA Interactions.International journal of molecular sciences · 2021
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah C PyfromDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-3781-6463
Chaz C QuinnDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Hannah K DorandoDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-9600-588X
Hong LuoDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Jacqueline E PaytonDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110 jpayton@wustl.edu.ORCID 0000-0001-8832-3661
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
NATIONAL RESEARCH SERVICE AWARD-MEDICAL SCIENTISTT32GM007200 · NIGMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 1985 to 2024
$59.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
TARGETING EPIGENOMIC SIGNATURES IN NON-HODGKIN LYMPHOMA FOR NOVEL THERAPEUTICSR01CA156690 · NCI · WASHINGTON UNIVERSITY · PI OLTZ, EUGENE M, PAYTON, JACQUELINE E. · 2010 to 2014
$3.1M
SEQUENCE-SPECIFIC CHROMATIN MODIFIERS; NOVEL PROTEIN THERAPEUTICS FOR B CELL LYMPHOMAR01CA188286 · NCI · WASHINGTON UNIVERSITY · PI OLTZ, EUGENE M, PAYTON, JACQUELINE E. · 2015 to 2019
$1.7M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA156690NCI NIH HHS R01 CA188286NIGMS NIH HHS T32 GM007200
6 · The paper itself

Abstract

Of the thousands of long noncoding RNAs (lncRNA) identified in lymphocytes, very few have defined functions. In this study, we report the discovery and functional elucidation of a human B cell-specific lncRNA with high levels of expression in three types of B cell cancer and normal B cells. The

Indexed as

AdultAgedAged, 80 and overA Kinase Anchor ProteinsB-LymphocytesCalcium SignalingCell LineCytoskeletal ProteinsFemaleHumansMaleMiddle AgedMinor Histocompatibility AntigensPhospholipase C gammaPhospholipase DProtein Tyrosine Phosphatase, Non-Receptor Type 6AKAP13 protein, humanAKAP9 protein, humanA Kinase Anchor ProteinsCytoskeletal ProteinsMinor Histocompatibility AntigensPhospholipase C gammaPhospholipase Dphospholipase D1PLCG2 protein, humanProtein Tyrosine Phosphatase, Non-Receptor Type 6Proto-Oncogene ProteinsPTPN6 protein, humanReceptors, Antigen, B-CellRNA, Long Noncoding

Identifiers

PMID32571842
PMCPMC7372127
OpenAlexW3036889400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.