ArticleStroke and vascular neurology2021
Management characteristics and prognosis after stroke in China: findings from a large nationwide stroke registry.
Article in Stroke and vascular neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Projections of the global, regional and national stroke burden by 2050: a systematic analysis for the Global Burden of Disease Study 2021.European journal of epidemiology · 2026Article
- Outcome selection of randomized controlled trials in acute stroke: a comparative analysis between traditional Chinese medicine and Western medicine.Frontiers in medicine · 2026Review
- Association of cardiometabolic index and new-onset stroke in middle-aged and elderly Chinese: a national prospective cohort study.BMC neurology · 2025Article
- Health Belief Clusters Among Stroke Patients: Insights for Tailored Interventions Using Latent Profile Analysis.Patient preference and adherence · 2025Article
- Determinants of hospital length of stay in ischemic stroke patients: A retrospective cohort study at Indonesian national stroke center.PloS one · 2025Article
- Efficacy of midnight-noon Ebb-flow hour-prescription method combined with acupuncture at Baihui Bazhen acupoints in the rehabilitation of Aphasia after ischemic stroke.African health sciences · 2024Article
- Low Remnant Cholesterol and In-Hospital Bleeding Risk After Ischemic Stroke or Transient Ischemic Attack.Journal of the American Heart Association · 2024Article
- Association Between Body Mass Index and Functional Outcomes in Patients With Intracerebral Hemorrhage.Neurology · 2024Article
- Prognostic model of in-hospital ischemic stroke mortality based on an electronic health record cohort in Indonesia.PloS one · 2024Observational
- Clinical Potential of Immunotherapies in Subarachnoid Hemorrhage Treatment: Mechanistic Dissection of Innate and Adaptive Immune Responses.Aging and disease · 2023Review
- Loss of life expectancy due to stroke and its subtypes in urban and rural areas in China, 2005-2020.Stroke and vascular neurology · 2023Article
- Independent Predictive Value of Elevated YKL-40 in Ischemic Stroke Prognosis: Findings from a Nationwide Stroke Registry.Cerebrovascular diseases (Basel, Switzerland) · 2023Article
- CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats.Stroke and vascular neurology · 2022Article
- Association of triglyceride-glucose index and stroke recurrence among nondiabetic patients with acute ischemic stroke.BMC neurology · 2022Article
- Genetic variation within the pri-let-7f-2 in the X chromosome predicting stroke risk in a Chinese Han population from Liaoning, China: From a case-control study to a new predictive nomogram.Frontiers in medicine · 2022Article
- Body mass index and clinical outcomes in patients with intracerebral haemorrhage: results from the China Stroke Center Alliance.Stroke and vascular neurology · 2021Article
- Variations of risk factors for ischemic stroke and its subtypes in Chinese patients in Taiwan.Scientific reports · 2021Article
- China Stroke Registry for Patients With Traditional Chinese Medicine (CASES-TCM): Rationale and Design of a Prospective, Multicenter, Observational Study.Frontiers in pharmacology · 2021Review
- Stroke History is an Independent Risk Factor for Poor Prognosis in Ischemic Stroke Patients: Results from a Large Nationwide Stroke Registry.Current neurovascular research · 2020Article
- Serial serum calcium dynamics predict delayed hydrocephalus after spontaneous subarachnoid hemorrhage: development and validation of a clinical nomogram in an observational cohort.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
background and purposeThere is limited nationwide evidence about the standard management characteristics of stroke types and prognosis in China. This study aimed to assess clinical characteristics, in-hospital and after-discharge management characteristics and prognosis for stroke types in China.
methodsA nationwide registry recruited 14 244 imaging-confirmed first-ever incident strokes from 132 hospitals across 31 provinces of China during 2007-2008, recording presenting characteristics, diagnostic procedures and in-hospital treatment. After hospital discharge, patients were followed up for 6 months. Conventional statistical methods were used to examine the patterns of management and prognosis.
resultsOverall, 68.7%, 26.9% and 4.4% were ischaemic stroke (IS), intracerebral haemorrhage (ICH), and subarachnoid haemorrhage (SAH), respectively. Only 20% were managed in a dedicated stroke unit. Among IS, 1.3% received thrombolysis within 3 hours after symptom onset, whereas the proportions of receiving in-hospital antiplatelet therapy, neuroprotective agents and traditional Chinese medicines (TCM) were 88.4%, 69.7% and 70.6%, respectively. For ICH, 63.3% and 36.3% received neuroprotective agents and TCM in hospital, respectively. At discharge, 70.7% and 38.0% of the patients with IS were given antiplatelet and statin therapies, respectively, decreasing to 64.8% and 23.9%, respectively, at 6 months. In-hospital mortality was 3.2%, 9.3% and 10.1% for IS, ICH and SAH, respectively, with a further 8.6%, 18.2% and 22.0%, respectively, died by 6 month. Meanwhile, in-hospital recurrence rate was 2.6%, 1.9% and 7.2% for IS, ICH and SAH, respectively, with a further 8.0%, 5.1% and 7.5%, respectively, recurred by 6 month.
conclusionsIn China, the mortality rate of stroke is lower than that reported from west populations, though most strokes are not managed in specialised stroke unit. There is widespread use of some unproven therapies but limited proven treatments, especially after discharge, leading to unnecessary recurrent risks.
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