Evidence map›Paper›PMID 32571791›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2020

Population-based Screening for

Jenny E Chu, Benny Johnson, Laveniya Kugathasan, Van K Morris, Kanwal Raghav, Lucas Swanson, Howard J Lim, Daniel J Renouf, Sharlene Gill, Robert Wolber and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 41 citations in OpenAlex.

  1. Phase Ib/II Study of Cetuximab plus Pembrolizumab in Patients with Advanced RAS Wild-Type Colorectal Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Trial
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  18. Current Targeted Therapy for Metastatic Colorectal Cancer.International journal of molecular sciences · 2023
    Review
  19. Article
  20. New developments in targeted therapy for metastatic colorectal cancer.Therapeutic advances in medical oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Jenny E ChuDepartment of Pathology and Laboratory Medicine, Vancouver Coastal Health Authority, Vancouver, British Columbia, Canada.ORCID 0000-0002-1841-3175
Benny JohnsonThe University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-3683-8115
Laveniya KugathasanBC Cancer, Vancouver, British Columbia, Canada.
Van K MorrisThe University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-4911-2252
Kanwal RaghavThe University of Texas MD Anderson Cancer Center, Houston, Texas.
Lucas SwansonThe University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-7074-4991
Howard J LimBC Cancer, Vancouver, British Columbia, Canada.
Daniel J RenoufBC Cancer, Vancouver, British Columbia, Canada.
Sharlene GillBC Cancer, Vancouver, British Columbia, Canada.
Robert WolberDepartment of Pathology and Laboratory Medicine, Vancouver Coastal Health Authority, Vancouver, British Columbia, Canada.
Aly KarsanDepartment of Pathology and Laboratory Medicine, Vancouver Coastal Health Authority, Vancouver, British Columbia, Canada.ORCID 0000-0001-6753-892X
Scott KopetzThe University of Texas MD Anderson Cancer Center, Houston, Texas.
David F SchaefferDepartment of Pathology and Laboratory Medicine, Vancouver Coastal Health Authority, Vancouver, British Columbia, Canada.
Jonathan M LoreeBC Cancer, Vancouver, British Columbia, Canada. jonathan.loree@bccancer.bc.ca.ORCID 0000-0001-8189-2132
Spinal Cord Injury BC · CAThe University of Texas MD Anderson Cancer Center · USVancouver Coastal Health · CA

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Project 3: Inhibiting Oxidative Phosphorylation in Pancreatic CancerP50CA221707 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KOPETZ, SCOTT, MAITRA, ANIRBAN · 2019 to 2023
$11.0M
Therapeutic Strategies for Patients With BRAF Mutant Colorectal CancerR01CA187238 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HONG, DAVID S., KOPETZ, SCOTT · 2014 to 2018
$1.7M
Stress Signaling Pathways and Resistance in Colorectal CancerR01CA172670 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KOPETZ, SCOTT · 2013 to 2017
$1.6M
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA221707NCI NIH HHS R01 CA172670NCI NIH HHS R01 CA187238
6 · The paper itself

Abstract

purposeEXPERIMENTAL

designWe reviewed a population-based cohort of 1,898 patients with colorectal cancer that underwent reflexive IHC mismatch repair (MMR) and

resultsAll-stage population prevalence of

conclusionsPatients with

Indexed as

AgedAged, 80 and overBiomarkers, TumorBiopsyColorectal NeoplasmsDNA Mismatch RepairFemaleGenetic TestingHumansMaleMass ScreeningMiddle AgedMolecular EpidemiologyMutationPrevalencePrognosisBiomarkers, TumorBRAF protein, humanProto-Oncogene Proteins B-raf

Identifiers

PMID32571791
PMCPMC7484131
OpenAlexW3036855997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.