Evidence map›Paper›PMID 32571756›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2020

The Dose-Response Relationship Between Physical Activity and Cardiometabolic Health in Young Adults.

Heather R Frank, Hillary Mulder, Karishma Sriram, Taruni S Santanam, Asheley C Skinner, Eliana M Perrin, Sarah C Armstrong, Eric D Peterson, Michael Pencina, Charlene A Wong

Open access · greenAbstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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  12. Public Health Implications of the Dose-Response Association Between Physical Activity and Cardiometabolic Health in Young Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Heather R FrankDuke University School of Medicine, Durham, North Carolina.
Hillary MulderDuke Clinical Research Institute, Durham, North Carolina.
Karishma SriramDuke University School of Medicine, Durham, North Carolina.
Taruni S SantanamDuke-Margolis Center for Health Policy, Duke University, Durham, North Carolina.
Asheley C SkinnerDuke Clinical Research Institute, Durham, North Carolina; Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina; Duke Center for Childhood Obesity Research, Duke University School of Medicine, Durham, North Carolina.
Eliana M PerrinDuke Center for Childhood Obesity Research, Duke University School of Medicine, Durham, North Carolina; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Sarah C ArmstrongDuke Clinical Research Institute, Durham, North Carolina; Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina; Duke Center for Childhood Obesity Research, Duke University School of Medicine, Durham, North Carolina; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Eric D PetersonDuke Clinical Research Institute, Durham, North Carolina.
Michael PencinaDuke Clinical Research Institute, Durham, North Carolina.
Charlene A WongDuke Clinical Research Institute, Durham, North Carolina; Duke Center for Childhood Obesity Research, Duke University School of Medicine, Durham, North Carolina; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina; Children's Health and Discovery Institute, Duke University School of Medicine, Durham, North Carolina. Electronic address: charlene.wong@duke.edu.
Duke University · USClinical Research Institute · US

Funding

Financial and Social Behavioral Economic Incentives to Increase Physical Activity in Adolescents and Young Adults for Cardiovascular HealthK23HL141689 · NHLBI · DUKE UNIVERSITY · PI WONG, CHARLENE · 2018 to 2019
$245k
NHLBI NIH HHS K23 HL141689
6 · The paper itself

Abstract

purposeGuidelines recommend 150 minutes of weekly moderate-to-vigorous physical activity (MVPA) for all adults, although physical activity level correlation with cardiometabolic health is not well characterized for young adults. We determined the dose-response relationship of MVPA on measures of cardiometabolic health in young adults.

methodsWe examined young adults (aged 20-29 years; N = 5,395, 47.9% female) in the 2003-2016 National Health and Nutrition Examination Survey. Exposures were objective (accelerometer based) and self-reported weekly mean minutes of MVPA. Cardiometabolic outcome measures were body mass index (BMI), high-density lipoprotein (HDL), total cholesterol, systolic blood pressure, and diastolic blood pressure. The dose-response relationships were assessed with unadjusted spline analyses. Sex-stratified outcomes were modeled using multivariable linear regression with mean estimated change presented for 150-minute dose increases of MVPA.

resultsAmong females, associations between objective activity and cardiometabolic measures were all linear. Compared with no activity, 150 minutes of objective activity was associated with a lower BMI (-1.37 kg/m

conclusionsThe dose-response relationships between physical activity and cardiometabolic markers in young adults were predominantly linear, supporting public health calls for any increase in physical activity in this population.

Indexed as

Cardiovascular DiseasesBlood PressureCross-Sectional StudiesExerciseFemaleHumansMaleNutrition SurveysRisk FactorsTriglyceridesWaist CircumferenceYoung AdultTriglyceridesCardiometabolic healthDose–response relationshipNatural cubic splinesPhysical activitySpline analysisYoung adults

Identifiers

PMID32571756
PMCPMC11218041
OpenAlexW3036087606

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.