Evidence map›Paper›PMID 32571406›Full record

ArticleBMC research notes2020

Qualitative and quantitative assay of glucose 6 phosphate dehydrogenase in patients attending tertiary care center.

Uday Sharma, Satyendra Mishra, Narayan Gautam, Badri Kumar Gupta

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Uday SharmaUniversal College of Medical Sciences, Bhairahawa, Nepal. udysharma1000@gmail.com.ORCID http://orcid.org/0000-0001-8651-777X
Satyendra MishraDepartment of Pathology, Universal College of Medical Sciences, Bhairahawa, Nepal.
Narayan GautamDepartment of Biochemistry, Universal College of Medical Sciences, Bhairahawa, Nepal.
Badri Kumar GuptaDepartment of Pediatrics, Universal College of Medical Sciences, Bhairahawa, Nepal.
College of Medical Sciences · NPUniversal College · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study was carried out with the aim to find out the frequency of Glucose 6 phosphate dehydrogenase (G6PD) deficiency among the patients attending the hospital and to rationalize the qualitative methemoglobin reduction test in reference to the quantitative spectrophotometric assay. Timely screening of the patients for G6PD with appropriate screening method can play an important role in preventing hemolytic crisis that arises from therapeutic use of oxidative drugs like primaquine.

resultThe frequency of G6PD deficient cases was 3% by both of the employed tests. The mean ± SD of G6PD activity in the patients under study was 15.34 ± 4.7 IU/g Hb in males and 16.01 ± 3.74 IU/g Hb in females. G6PD activity was positively associated with reticulocyte count (r = 0.289, p value = 0.004) and negatively with mean corpuscular hemoglobin concentration (r = -0.220, p-value = 0.028). The correlation of red blood corpuscular count and G6PD was statistically significant (p-value = 0.048).

Indexed as

AdolescentAdultChildChild, PreschoolClinical Enzyme TestsCross-Sectional StudiesFemaleGlucosephosphate DehydrogenaseGlucosephosphate Dehydrogenase DeficiencyHumansInfantMaleMethemoglobinMiddle AgedReticulocyte CountSpectrophotometryG6PD protein, humanGlucosephosphate DehydrogenaseMethemoglobinGlucose 6 phosphate dehydrogenaseHemolytic disordersMethemoglobin reduction testSpectrophotometric assay

Identifiers

PMID32571406
PMCPMC7310380
OpenAlexW3036204163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.