ArticleBMC ophthalmology2020
Lhasa childhood eye study: the rationale, methodology, and baseline data of a 5 year follow-up of school-based cohort study in the Tibetan plateau region of Southwest China.
Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Retinal Vascular Caliber and Its Ocular and Systemic Correlates in Children Living at High Altitude.Children (Basel, Switzerland) · 2026Article
- Factors influencing image quality in Tibetan children by optical coherence tomography.Frontiers in medicine · 2025Article
- Assessment of macular choroidal and retinal thickness: a cohort study in Tibetan healthy children.Scientific reports · 2024Article
- Evaluation of childhood developingWorld journal of clinical cases · 2023Article
- Baseline Refractive Error, Habitual Accommodative Tone, and Its Association With Myopia in Children: The Lhasa Childhood Eye Study.Investigative ophthalmology & visual science · 2023Article
- Paediatric vision screening in Urban Lhasa from the Tibetan Plateau of Southwest China.Eye (London, England) · 2023Article
- Stereoacuity and its determinants in 7-year-old children: the Lhasa Childhood Eye Study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Distribution, Progression, and Associated Factors of Refractive Status of Children in Lhasa, Tibet, after COVID-19 Quarantine.Ophthalmic research · 2022Article
- Pinhole does not increase screening accuracy of detecting decreased best corrected visual acuity in schoolchildren.BMC ophthalmology · 2021Article
- Prevalence and pattern of refractive error and visual impairment among schoolchildren: the Lhasa childhood eye study.BMC ophthalmology · 2021Article
- Difference of refractive status before and after cycloplegic refraction: the Lhasa Childhood Eye Study.Japanese journal of ophthalmology · 2021Article
- Correction to: Lhasa childhood eye study: the rationale, methodology, and baseline data of a 5 year follow-up of school-based cohort study in the Tibetan plateau region of Southwest China.BMC ophthalmology · 2020Article
- Prevalence of Heterophoria in Tibetan Grade-One Students: The Lhasa Childhood Eye Study.Journal of ophthalmology · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
backgroundTibetan Plateau is a highland area with special geographical location, time zone, and ethnic composition. We herein report the rationale, methodology and baseline data of the school-based childhood cohort study named Lhasa Childhood Eye Study (LCES), with the primary objective to pursue a comprehensive understanding on the longitudinal trends of refractive error as well as other ocular diseases and to address the differences between Tibetan Plateau and other parts of the world.
methodsGrade one students from primary schools in Lhasa were cluster randomly selected. They were examined and would be conducted with follow-up annually for 5 years. The examination procedures for LCES consisted of standardized ocular, systematic examinations, and questionnaires, identical to the Anyang Childhood Eye Study (ACES) conducted in central China.
resultsOne thousand nine hundred two Grade one students eligible for the LCES, 1856 (97.58%) participated in the study, with a mean age of 6.83 ± 0.46 years (range 5.89-10.32 years), and the proportions of male to be 53.02%. 1762 (94.93%) of the 1856 participants in the baseline exam were Tibetans. 1837 (98.98%) of the students examined had cycloplegic autorefraction performed. The numbers of hyperopia, emmetropia, myopia, and high myopia were 127 (6.91%), 1639 (89.22%), 71 (3.86%) and 3 (0.16%) respectively. Compared with ACES, students from LCES baseline had a younger age (p < 0.001), lower cycloplegic spherical equivalent (p < 0.001), similar myopia prevalence (p = 0.886), lower hyperopia prevalence (p < 0.001), and a higher emmetropia prevalence (p < 0.001).
conclusionsLCES was a school-based cohort study in Tibetan Plateau with a high baseline response rate. A higher emmetropic trend was found in LCES compared with ACES. Continuous documentation of this cohort might potentially provide useful reference information for the areas of China which was previously not well studied.
trial registrationThe study has finished the clinical registration on Chinese Clinical Trial Registry. (ChiCTR1900026693).
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