Evidence map›Paper›PMID 32571233›Full record

ArticleBMC infectious diseases2020

Fungal arthritis with adjacent osteomyelitis caused by Candida pelliculosa: a case report.

Kwang Yun Song, Chulmin Park, Ji-Hyun Byun, Hye-Sun Chun, Jung-Hyun Choi, Eun Hee Han, Seung Ok Lee, Yeonjeong Jeong, Youn Jeong Kim, Si-Hyun Kim

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kwang Yun SongDepartment of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Chulmin ParkVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ji-Hyun ByunVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hye-Sun ChunVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jung-Hyun ChoiVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Eun Hee HanDepartment of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Seung Ok LeeDepartment of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yeonjeong JeongDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Youn Jeong KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Si-Hyun KimVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. ksihyun@catholic.ac.kr.ORCID http://orcid.org/0000-0002-6392-0221
Catholic University of Korea · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KR

Funding

The Catholic Medical Center Research Foundation Program year of 2017
6 · The paper itself

Abstract

backgroundCandida sp. osteoarticular infection is rare and most often due to hematogenous seeding during an episode of candidemia in immunocompromised patients. However, the diagnosis can be delayed in patients with subtle symptoms and signs of joint infection without a concurrent episode of candidemia. CASE PRESENTATION: A 75-year-old woman presented with a three-year history of pain and swelling of the left knee. Candida pelliculosa was detected from the intraoperative tissue when the patient had undergone left total knee arthroplasty 32 months ago, but no antifungal treatment was performed. One year after the total knee arthroplasty, C. pelliculosa was repeatedly isolated from the left knee synovial fluid and antifungal treatment comprising amphotericin B deoxycholate and fluconazole was administered. However, joint infection had extended to the adjacent bone and led to progressive joint destruction. The patient underwent surgery for prosthesis removal and received prolonged antifungal treatment with micafungin and fluconazole.

conclusionsThis case shows that C. pelliculosa, an extremely rare non-Candida albicans sp., can cause fungal arthritis and lead to irreversible joint destruction owing to delayed diagnosis and treatment.

Indexed as

AgedAmphotericin BAntifungal AgentsArthritis, InfectiousArthroplasty, Replacement, KneeCandidaCandidemiaCandidiasisDeoxycholic AcidDevice RemovalDrug CombinationsFemaleFluconazoleHumansIntraoperative CareJoint ProsthesisAmphotericin Bamphotericin B, deoxycholate drug combinationAntifungal AgentsDeoxycholic AcidDrug CombinationsFluconazoleMicafunginArthritisCandidaMicafunginOsteomyelitis

Identifiers

PMID32571233
PMCPMC7310117
OpenAlexW3036304378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.