ArticlePerfusion2020
Haemolysis induced by mechanical circulatory support devices: unsolved problems.
Article in Perfusion, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- In Vitro Comparison of Device-Induced Hemolysis, Platelet Defects, and von Willebrand Factor Degradation Between the HeartMate 2 and HeartMate 3 Pumps.Artificial organs · 2025Article
- Effects of sodium fluoride on serum concentrations of selected psychotropic drugs.Journal of forensic sciences · 2025Article
- Pre-bypass ultrafiltration reduces cytokine burden of blood prime in pediatric cardiac surgery.Scientific reports · 2025Observational
- Pump-Induced Hemolysis of Speed Modulated Axial-Flow Left Ventricular Assist Devices.Artificial organs · 2025Article
- Dynamic blood compatibility assessment of coronary stents using an innovative pneumatic blood pump to generate physiological flow rates in small sample chambers.Journal of materials science. Materials in medicine · 2025Article
- Mechanical Stimulation of Red Blood Cells Aging: Focusing on the Microfluidics Application.Micromachines · 2025Review
- Mechanically-foldable axial flow blood pump: response-surface-based structural optimization and hemolytic performance evaluation.Frontiers in physiology · 2025Article
- Analysis of non-physiological shear stress-induced red blood cell trauma across different clinical support conditions of the blood pump.Medical & biological engineering & computing · 2024Article
- Dynamic VAD simulations: Performing accurate simulations of ventricular assist devices in interaction with the cardiovascular system.The International journal of artificial organs · 2024Article
- Practical Comparison of Two- and Three-Phase Bearingless Permanent Magnet Slice Motors for Blood Pumps.Actuators · 2024Article
- Current and Future Engineering Strategies for ECMO Therapy.Advances in experimental medicine and biology · 2023Article
- Challenge of material haemocompatibility for microfluidic blood-contacting applications.Frontiers in bioengineering and biotechnology · 2023Review
- Acute Kidney Injury in Cardiogenic Shock: An Updated Narrative Review.Journal of cardiovascular development and disease · 2021Review
- Investigating the cause of hemolysis in patients supported by a pulsatile ventricular assist device.Heart and vessels · 2021Article
- Magnetic Particles with Polymeric Shells Bearing Cholesterol Moieties Sensitize Breast Cancer Cells to Low Doses of Doxorubicin.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the use of continuous flow blood pumps as ventricular assist devices is standard, the problems with haemolysis have increased. It is mainly induced by shear stress affecting the erythrocyte membrane. There are many investigations about haemolysis in laminar and turbulent blood flow. The results defined as threshold levels for the damage of erythrocytes depend on the exposure time of the shear stress, but they are very different, depending on the used experimental methods or the calculation strategy. Here, the results are resumed and shown in curves. Different models for the calculation of the strengths of erythrocytes are discussed. There are few results reported about tests of haemolysis in blood pumps, but some theoretical approaches for the design of continuous flow blood pumps according to low haemolysis have been investigated within the last years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.