Evidence map›Paper›PMID 32570959›Full record

ReviewPathogens (Basel, Switzerland)2020

COVID-19 in Pregnant Women and Neonates: A Systematic Review of the Literature with Quality Assessment of the Studies.

Giulia Trippella, Martina Ciarcià, Marta Ferrari, Chiara Buzzatti, Ilaria Maccora, Chiara Azzari, Carlo Dani, Luisa Galli, Elena Chiappini

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 6 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 6 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
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  17. Neurological effects of COVID-19 in infants and children.Developmental medicine and child neurology · 2022
    Review
  18. Article
  19. Review
  20. Maternal-fetal bonding during the COVID-19 pandemic.BMC pregnancy and childbirth · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giulia TrippellaPost-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence, 50100 Florence, Italy.
Martina CiarciàPost-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence, 50100 Florence, Italy.
Marta FerrariPost-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence, 50100 Florence, Italy.
Chiara BuzzattiPost-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence, 50100 Florence, Italy.
Ilaria MaccoraPost-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence, 50100 Florence, Italy.ORCID 0000-0001-6418-3254
Chiara AzzariDivision of Pediatric Immunology, Department of Health Sciences, University of Florence and Meyer Children's Hospital, 50100 Florence, Italy.
Carlo DaniDepartment of Neurosciences, Psychology, Drug Research and Children's Health, University of Florence, 50100 Florence, Italy.
Luisa GalliDivision of Pediatric Infectious Disease, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence,50100 Florence, Italy.ORCID 0000-0002-7912-3366
Elena ChiappiniDivision of Pediatric Infectious Disease, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence,50100 Florence, Italy.
Meyer Children's Hospital · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 virus emerged in December 2019 and then spread globally. Little is still known about the impact of COVID-19 on pregnant women and neonates. A review of the literature was performed according to the PRISMA guideline recommendations, searching the MEDLINE and EMBASE databases. Studies' quality assessments were performed using the JBI Critical Appraisal Checklist. A total of 37 studies were included, involving 275 pregnant women with COVID-19 and 248 neonates. The majority of pregnant women presented with mild to moderate symptoms, only 10 were admitted in the ICU, and one died. Two stillbirths were reported and the incidence of prematurity was 28%. Sixteen neonates were tested positive for SARS-CoV-2 by RT-PCR, and nine of them were born from mothers infected during pregnancy. Neonatal outcomes were generally good: all the affected neonates recovered. RT-PCR for SARS-CoV-2 yielded negative results on amniotic fluid, vaginal/cervical fluids, placenta tissue, and breast milk samples. SARS-CoV-2 infection in pregnant women appeared associated with mild or moderate disease in most cases, with a low morbidity and mortality rate. The outcomes of neonates born from infected women were mainly favorable, although neonates at risk should be closely monitored. Further studies are needed to investigate the possibility of vertical transmission.

Indexed as

COVID-19neonatespregnancySARS-CoV-2

Identifiers

PMID32570959
PMCPMC7350364
OpenAlexW3035767078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.