Evidence map›Paper›PMID 32570744›Full record

ArticleSensors (Basel, Switzerland)2020

A Compact Mid-Infrared Spectroscopy System for Healthcare Applications Based on a Wavelength-Swept, Pulsed Quantum Cascade Laser.

Takuya Koyama, Naoto Shibata, Saiko Kino, Atsushi Sugiyama, Naota Akikusa, Yuji Matsuura

Open access · goldAbstract readLetter
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Takuya KoyamaGraduate School of Biomedical Engineering, Tohoku University, Sendai 908-8579, Japan.
Naoto ShibataGraduate School of Biomedical Engineering, Tohoku University, Sendai 908-8579, Japan.
Saiko KinoGraduate School of Biomedical Engineering, Tohoku University, Sendai 908-8579, Japan.
Atsushi SugiyamaHamamatsu Photonics K.K., Hamamatsu 434-8601, Japan.
Naota AkikusaHamamatsu Photonics K.K., Hamamatsu 434-8601, Japan.ORCID 0000-0001-8915-3828
Yuji MatsuuraGraduate School of Biomedical Engineering, Tohoku University, Sendai 908-8579, Japan.ORCID 0000-0002-4722-7654
Tohoku University · JPHamamatsu Photonics (Japan) · JP

Funding

Japan Society for the Promotion of Science JP17H03242Japan Society for the Promotion of Science JP18K18842
6 · The paper itself

Abstract

A mid-infrared spectroscopic system using a high-speed wavelength-swept and pulsed quantum cascade laser (QCL) for healthcare applications such as blood glucose measurement is proposed. We developed an attenuated total reflection measurement system comprising the QCL with a micro-electromechanical system (MEMS)-scanning grating, hollow optical fibers, and InAsSb detector and tested its feasibility for healthcare applications. A continuous spectrum was obtained by integrating comb-shaped spectra, the timing of which was slightly shifted. As this method does not require complex calculations, absorption spectra are obtained in real-time. We found that the signal-to-noise ratio of the obtained spectrum had been improved by increasing the number of spectra that were integrated into the spectrum calculation. Accordingly, we succeeded in measuring the absorption spectrum of a 0.1% aqueous glucose solution. Furthermore, the absorption spectra of human lips were measured, and it was shown that estimation of blood glucose levels were possible using a model equation derived using a partial least squares regression analysis of the measured absorption spectra. The spectroscopic system based on the QCL with MEMS-scanning grating has the advantages of compactness and low cost over conventional Fourier transform infrared-based systems and common spectroscopic systems with a tunable QCL that has a relatively large, movable grating.

Indexed as

Delivery of Health CareLasers, SemiconductorOptical FibersHumansLeast-Squares AnalysisSpectrophotometry, InfraredATR spectroscopyhollow optical fibermid-infrared spectroscopyquantum cascade laser

Identifiers

PMID32570744
PMCPMC7349820
OpenAlexW3036706525

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.