Evidence map›Paper›PMID 32570704›Full record

ArticleBiomolecules2020

Role of Lipopolysaccharide in Protecting OmpT from Autoproteolysis during In Vitro Refolding.

Gaurav Sinsinbar, Sushanth Gudlur, Kevin J Metcalf, Milan Mrksich, Madhavan Nallani, Bo Liedberg

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gaurav SinsinbarCenter for Biomimetic Sensor Science, School of Materials Science and Engineering, Nanyang Technological University, Singapore 637553, Singapore.ORCID 0000-0001-7720-7198
Sushanth GudlurCenter for Biomimetic Sensor Science, School of Materials Science and Engineering, Nanyang Technological University, Singapore 637553, Singapore.
Kevin J MetcalfDepartments of Chemistry and Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Milan MrksichDepartments of Chemistry and Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Madhavan NallaniCenter for Biomimetic Sensor Science, School of Materials Science and Engineering, Nanyang Technological University, Singapore 637553, Singapore.
Bo LiedbergCenter for Biomimetic Sensor Science, School of Materials Science and Engineering, Nanyang Technological University, Singapore 637553, Singapore.ORCID 0000-0003-2883-6953
Nanyang Technological University · SGNorthwestern University · US

Funding

Cancer Nanotechnology Training ProgramT32CA186897 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLOSCHAK, GAYLE E. · 2015 to 2019
$1.2M
NCI NIH HHS T32 CA186897NIH/NCI training grant 5T32CA186897-02NTU-NU Institute for NanoMedicine Agmt10/20/14Singapore Ministry of Education Academic Research Fund Tier 2 MOE2018-T2-1-025
6 · The paper itself

Abstract

Outer membrane protease (OmpT) is a 33.5 kDa aspartyl protease that cleaves at dibasic sites and is thought to function as a defense mechanism for

Indexed as

Bacterial Outer Membrane ProteinsEscherichia coliEscherichia coli ProteinsLipopolysaccharidesModels, MolecularPeptide HydrolasesProtein RefoldingProteolysisRecombinant ProteinsBacterial Outer Membrane ProteinsEscherichia coli ProteinsLipopolysaccharidesompT protein, E coliPeptide HydrolasesRecombinant ProteinsautoproteolysisE. coliheat modifiable proteinLPSOmpTomptin familyouter membrane protease

Identifiers

PMID32570704
PMCPMC7356225
OpenAlexW3036381845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.