Evidence map›Paper›PMID 32569446›Full record

ArticleEMBO molecular medicine2020

Can artificial intelligence identify effective COVID-19 therapies?

Michael B Schultz, Daniel Vera, David A Sinclair

Abstract readComment
In one paragraph

Article in EMBO molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Paving New Roads UsingIranian journal of pharmaceutical research : IJPR · 2022
    Review
  3. Review
  4. Application Progress of Organoids in Colorectal Cancer.Frontiers in cell and developmental biology · 2022
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Observational
  12. Severe Acute Respiratory Distress Syndrome Secondary to Coronavirus 2 (SARS-CoV-2).The international journal of occupational and environmental medicine · 2020
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Michael B SchultzPaul F. Glenn Center for Biology of Aging Research, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Daniel VeraPaul F. Glenn Center for Biology of Aging Research, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
David A SinclairPaul F. Glenn Center for Biology of Aging Research, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-9936-436X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of EMBO Molecular Medicine, Stebbing et al (2020b) validate an artificial intelligence-assisted prediction that a drug used to treat rheumatoid arthritis could be a potent weapon against COVID-19. Using liver organoids infected with SARS-CoV-2, they confirm dual antiviral and anti-inflammatory activities and show that its administration in four COVID-19 patients is correlated with disease improvement, paving the way for more rigorous placebo-controlled trials.

Indexed as

BetacoronavirusCoronavirus InfectionsPandemicsPneumonia, ViralArtificial IntelligenceAzetidinesCOVID-19HumansPurinesPyrazolesSARS-CoV-2SulfonamidesAzetidinesbaricitinibPurinesPyrazolesSulfonamides

Identifiers

PMID32569446
PMCPMC7361072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.