Evidence map›Paper›PMID 32569327›Full record

ArticlePloS one2020

FasTag: Automatic text classification of unstructured medical narratives.

Guhan Ram Venkataraman, Arturo Lopez Pineda, Oliver J Bear Don't Walk Iv, Ashley M Zehnder, Sandeep Ayyar, Rodney L Page, Carlos D Bustamante, Manuel A Rivas

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guhan Ram VenkataramanDepartment of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, United States of America.
Arturo Lopez PinedaDepartment of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, United States of America.
Oliver J Bear Don't Walk IvDepartment of Biomedical Informatics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States of America.
Ashley M ZehnderFauna Bio, San Francisco, CA, United States of America.
Sandeep AyyarDepartment of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, United States of America.
Rodney L PageDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States of America.
Carlos D BustamanteDepartment of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, United States of America.
Manuel A RivasDepartment of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, United States of America.ORCID 0000-0003-1457-9925

Funding

POSTDOCTORAL TRAINING IN MEDICAL INFORMATION SCIENCEST15LM007033 · NLM · STANFORD UNIVERSITY · PI SYLVIA KATINA PLEVRITIS · 1985 to 2026
$25.5M
Optimizing imputation for diverse populations in a distributed frameworkU01HG009080 · NHGRI · STANFORD UNIVERSITY · PI KENNY, EIMEAR ELIZABETH · 2016 to 2020
$5.2M
SOFTWARE FOR LARGE-SCALE INFERENCE OF THE GENETICS OF LIFESTYLE MEASURES, BIOMARKERS, AND COMMON AND RARE DISEASESR01HG010140 · NHGRI · STANFORD UNIVERSITY · PI KUNDAJE, ANSHUL, MONTGOMERY, STEPHEN · 2018 to 2022
$2.0M
NHGRI NIH HHS R01 HG010140NHGRI NIH HHS U01 HG009080NLM NIH HHS T15 LM007033
6 · The paper itself

Abstract

Unstructured clinical narratives are continuously being recorded as part of delivery of care in electronic health records, and dedicated tagging staff spend considerable effort manually assigning clinical codes for billing purposes. Despite these efforts, however, label availability and accuracy are both suboptimal. In this retrospective study, we aimed to automate the assignment of top-level International Classification of Diseases version 9 (ICD-9) codes to clinical records from human and veterinary data stores using minimal manual labor and feature curation. Automating top-level annotations could in turn enable rapid cohort identification, especially in a veterinary setting. To this end, we trained long short-term memory (LSTM) recurrent neural networks (RNNs) on 52,722 human and 89,591 veterinary records. We investigated the accuracy of both separate-domain and combined-domain models and probed model portability. We established relevant baseline classification performances by training Decision Trees (DT) and Random Forests (RF). We also investigated whether transforming the data using MetaMap Lite, a clinical natural language processing tool, affected classification performance. We showed that the LSTM-RNNs accurately classify veterinary and human text narratives into top-level categories with an average weighted macro F1 score of 0.74 and 0.68 respectively. In the "neoplasia" category, the model trained on veterinary data had a high validation accuracy in veterinary data and moderate accuracy in human data, with F1 scores of 0.91 and 0.70 respectively. Our LSTM method scored slightly higher than that of the DT and RF models. The use of LSTM-RNN models represents a scalable structure that could prove useful in cohort identification for comparative oncology studies. Digitization of human and veterinary health information will continue to be a reality, particularly in the form of unstructured narratives. Our approach is a step forward for these two domains to learn from and inform one another.

Indexed as

Data MiningNarrative MedicineSoftwareAnimalsAutomationDatabases as TopicHumansReproducibility of ResultsSpecies Specificity

Identifiers

PMID32569327
PMCPMC7307763

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.