Evidence map›Paper›PMID 32569272›Full record

ArticlePloS one2020

An instrument to assess HIV-related knowledge and adjustment to HIV+ status, and their association with anti-retroviral adherence.

M Barton Laws, Yoojin Lee, William S Rogers, Tatiana Taubin, Ira B Wilson

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M Barton LawsDept., of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, United States of America.ORCID 0000-0002-0790-5879
Yoojin LeeDept., of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, United States of America.
William S RogersInstitute for Clinical Research and Health Policy Studies, Tufts University, Boston, MA, United States of America.
Tatiana TaubinDept., of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, United States of America.
Ira B WilsonDept., of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, United States of America.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI ROUNDS, SHARON IRENE SMITH · 2016 to 2025
$45.0M
Explanatory models of illness and decision heuristics in HIV careR21MH092781 · NIMH · BROWN UNIVERSITY · PI LAWS, MICHAEL BARTON · 2011 to 2012
$472k
NIAID NIH HHS P30 AI042853NIGMS NIH HHS U54 GM115677NIMH NIH HHS R21 MH092781
6 · The paper itself

Abstract

backgroundFindings on the association between health literacy and anti-retroviral (ARV) adherence are inconsistent. Health literacy is usually operationalized with simple tests of basic literacy, but more complex conceptions of health literacy include content knowledge. People living with chronic illness also conceptualize and experience illness in ways other than biomedical or mechanistic models of disease.

objectiveThere are no instruments that comprehensively assess knowledge of people living with HIV concerning HIV disease and treatment; or psychological adjustment to being HIV+. Little is known about the relationship between factual knowledge, or positive identification as HIV+, and anti-retroviral (ARV) adherence.

methodsFormative work with in-depth semi-structured interviews, and cognitive testing, to develop a structured instrument assessing HIV-related knowledge, and personal meanings of living with HIV. Pilot administration of the instrument to a convenience sample of 101 respondents. KEY

resultsRespondents varied considerably in their expressed need for in-depth knowledge, the accuracy of their understanding of relevant scientific concepts and facts about ARV treatment, and psychological adjustment and acceptance of HIV+ status. Most knowledge domains were not significantly related to self-reported ARV adherence, but accurate knowledge specifically about ARV treatment was (r = 0.25, p = .02), as was an adapted version of the Need for Cognition scale (r = .256, p = .012). Negative feelings about living with HIV (r = .33, p = .0012), and medication taking (r = .276, p = .008) were significantly associated with non-adherence.

conclusionThe instrument may be useful in diagnosing addressable reasons for non-adherence, as a component of psychoeducational interventions, and for evaluation of such interventions.

Indexed as

Drug MonitoringHealth Knowledge, Attitudes, PracticeAdolescentAdultAgedAnti-HIV AgentsCognitionFemaleHIV InfectionsHumansMaleMedication AdherenceMiddle AgedYoung AdultAnti-HIV Agents

Identifiers

PMID32569272
PMCPMC7307754

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.