ArticleMedicine2020
Unilateral versus bilateral balloon kyphoplasty in treatment of osteoporotic vertebral compression fractures: A randomized controlled trial protocol.
Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- In-depth meta-analysis: unilateral PKP demonstrates significant advantages in treating osteoporotic vertebral compression fractures-an expanded RCT study with GRADE scoring.Frontiers in surgery · 2025Pooled it
- Unilateral Percutaneous Curved Kyphoplasty versus Bilateral Percutaneous Kyphoplasty for the Treatment of Single-Level Osteoporotic Vertebral Compression Fractures: A Retrospective Comparative Study.Journal of pain research · 2025Article
- Long-term therapeutic effect of percutaneous kyphoplasty combined with & without back muscle rehabilitation exercise in elderly patients. A comparative study.Pakistan journal of medical sciencesArticle
- Effects of high viscosity bone cement percutaneous vertebroplasty on pain, bone specific alkaline phosphatase, Type-I collage cross-linked-telopeptide and Boneglaprotein levels in patients with osteoporotic vertebral compression fractures.Pakistan journal of medical sciencesArticle
Corrections and comments
- Expression of concern
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is currently controversial whether unilateral or bilateral balloon kyphoplasty (BKP) is superior in terms of postoperative outcomes in treatment of osteoporotic vertebral compression fracture (OVCF). In this context, the aim of this study was to prospectively evaluate and compare the radiographic and clinical outcomes of BKP using unilateral and bilateral approaches.
methodsThis was a randomized controlled study and was approved by the Severance Institutional Review Board in our hospital. The study protocol was designed in accordance with the Declaration of Helsinki guidelines. Patients who complained of chronic back pain secondary to OVCF, which occurred in thoracic lumbar region over 6 months and met the criteria of osteoporosis were the candidates for this procedure. A total of 150 patients were randomized to undergo either unilateral or bipedicular BKP. The outcomes measures inculded pain score, Oswestry Dysfunction Index, compression ratio, kyphotic angle, operation time, and postoperative complications.
resultsWe were able to directly compare the outcomes of unilateral versus bilateral BKP and might reveal a better technique in OVCF.
trial registrationthis study protocol was registered in Research Registry (researchregistry5543).
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Registered trials
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