Evidence map›Paper›PMID 32568676›Full record

ArticleComputers in biology and medicine2020

Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: Results of 10 convolutional neural networks.

Ali Abbasian Ardakani, Alireza Rajabzadeh Kanafi, U Rajendra Acharya, Nazanin Khadem, Afshin Mohammadi

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Computers in biology and medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04750330 (Mitochondrial DNA and Nuclear SNPs to Predict Severity of COVID-19 Infection), which is not on this map. Cited by 307 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
307citing papers in PubMed, 8 pooled it
84.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04750330 completednot on this mapstarted 2021, after this paper: background citation

Mitochondrial DNA and Nuclear SNPs to Predict Severity of COVID-19 Infection

TypeobservationalSponsorMaastricht UniversityRan2021 to 2023Enrolled394ConditionsCovid19
3 · Its place in the literature

Who cites it

307 citing papers in PubMed, 8 syntheses or guidelines pooled it, 877 citations in OpenAlex.

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  8. Role of Artificial Intelligence in COVID-19 Detection.Sensors (Basel, Switzerland) · 2021
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  10. Performance of AI Approaches for COVID-19 Diagnosis Using Chest CT Scans: The Impact of Architecture and Dataset.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2026
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247 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Ali Abbasian ArdakaniMedical Physics Department, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran. Electronic address: A.ardekani@live.com.
Alireza Rajabzadeh KanafiDepartment of Radiology, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran. Electronic address: Alireza_r245@yahoo.com.
U Rajendra AcharyaDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore; Department of Biomedical Engineering, School of Science and Technology, Singapore University of Social Sciences, Singapore; School of Medicine, Faculty of Health and Medical Sciences, Taylor's University, 47500, Subang Jaya, Malaysia; Department of Biomedical Informatics and Medical Engineering, Asia University, Taiwan. Electronic address: aru@np.edu.sg.
Nazanin KhademDepartment of Radiology, Faculty of Medicine, Urmia University of Medical Science, Urmia, Iran. Electronic address: Nazanin.khadem74@gmail.com.
Afshin MohammadiDepartment of Radiology, Faculty of Medicine, Urmia University of Medical Science, Urmia, Iran. Electronic address: Afshin.mohdi@gmail.com.
Urmia University · IRGuilan University of Medical Sciences · IRIran University of Medical Sciences · IRSingapore University of Social Sciences · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fast diagnostic methods can control and prevent the spread of pandemic diseases like coronavirus disease 2019 (COVID-19) and assist physicians to better manage patients in high workload conditions. Although a laboratory test is the current routine diagnostic tool, it is time-consuming, imposing a high cost and requiring a well-equipped laboratory for analysis. Computed tomography (CT) has thus far become a fast method to diagnose patients with COVID-19. However, the performance of radiologists in diagnosis of COVID-19 was moderate. Accordingly, additional investigations are needed to improve the performance in diagnosing COVID-19. In this study is suggested a rapid and valid method for COVID-19 diagnosis using an artificial intelligence technique based. 1020 CT slices from 108 patients with laboratory proven COVID-19 (the COVID-19 group) and 86 patients with other atypical and viral pneumonia diseases (the non-COVID-19 group) were included. Ten well-known convolutional neural networks were used to distinguish infection of COVID-19 from non-COVID-19 groups: AlexNet, VGG-16, VGG-19, SqueezeNet, GoogleNet, MobileNet-V2, ResNet-18, ResNet-50, ResNet-101, and Xception. Among all networks, the best performance was achieved by ResNet-101 and Xception. ResNet-101 could distinguish COVID-19 from non-COVID-19 cases with an AUC of 0.994 (sensitivity, 100%; specificity, 99.02%; accuracy, 99.51%). Xception achieved an AUC of 0.994 (sensitivity, 98.04%; specificity, 100%; accuracy, 99.02%). However, the performance of the radiologist was moderate with an AUC of 0.873 (sensitivity, 89.21%; specificity, 83.33%; accuracy, 86.27%). ResNet-101 can be considered as a high sensitivity model to characterize and diagnose COVID-19 infections, and can be used as an adjuvant tool in radiology departments.

Indexed as

BetacoronavirusDeep LearningNeural Networks, ComputerAdultAgedAged, 80 and overArtificial IntelligenceComputational BiologyCoronavirus InfectionsCOVID-19FemaleHumansLungMaleMiddle AgedPandemicsComputed tomographyCoronavirus infectionsCOVID-19Deep learningLung diseasesMachine learningPneumonia

Identifiers

PMID32568676
PMCPMC7190523
OpenAlexW3017644243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.