ReviewJournal of Parkinson's disease2020
Challenges and Perspectives in the Management of Late-Stage Parkinson's Disease.
Review in Journal of Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Feasibility and potential effectiveness of an exergame program for people with moderate to advanced Parkinson's disease: A pilot randomized controlled trial.Journal of Parkinson's disease · 2026Trial
- Clinical trials in late-stage Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Symptom prevalence and pharmacological management of late-stage Parkinson's disease (LSPD): a cross-sectional, multinational survey.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Non-pharmacological and non-surgical therapies in advanced Parkinson's disease: a narrative review and call to action.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Risk-Benefit Considerations in Deep Brain Stimulation Discontinuation for Late-Stage Parkinson's Disease.Movement disorders clinical practice · 2026Article
- Improving Advance Care Planning for People with Parkinson's.Movement disorders clinical practice · 2026Article
- A glimpse of the end-of-life of people with Parkinson's disease and atypical parkinsonism: A descriptive analysis of electronic health records.Journal of Parkinson's disease · 2025Article
- Far from being the end of the road: taking a closer look at neuropalliative care in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Disease-modifying, multidimensional efficacy of putaminal CaMolecular therapy : the journal of the American Society of Gene Therapy · 2025Article
- Hospital utilization and telemedicine preferences in patients with late-stage Parkinson's disease and caregivers.Clinical parkinsonism & related disorders · 2025Article
- Changes in the correlation between substantia nigra hyperechogenicity area and Parkinson's disease severity at different Hoehn and Yahr stages.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Multidisciplinary care in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- How to Use the New European Academy of Neurology/Movement Disorder Society European Section Guideline for Invasive Therapies in Parkinson's Disease.Movement disorders clinical practice · 2024Review
- Research progress on the application of anti-gravity treadmill in the rehabilitation of Parkinson's disease patients: a mini review.Frontiers in neurology · 2024Review
- A Glance at Biogenesis and Functionality of MicroRNAs and Their Role in the Neuropathogenesis of Parkinson's Disease.Oxidative medicine and cellular longevity · 2023Review
- Pulmonary function and medication effect in mild-stage subjects with Parkinson's disease.Arquivos de neuro-psiquiatria · 2022Article
- Peer Mentoring Program for Informal Caregivers of Homebound Individuals With Advanced Parkinson Disease (Share the Care): Protocol for a Single-Center, Crossover Pilot Study.JMIR research protocols · 2022Article
- Personalized Care in Late-Stage Parkinson's Disease: Challenges and Opportunities.Journal of personalized medicine · 2022Review
- Caregiver Burden and Quality of Life in Late Stage Parkinson's Disease.Brain sciences · 2022Article
- Analysis of Transition of Patients with Parkinson's Disease into Institutional Care: A Retrospective Pilot Study.Brain sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease (PD) is a common neurodegenerative disorder, with a continuously increasing prevalence. With improved clinical and therapeutic management of PD, more patients reach later stages of the disease, meaning they may face new clinical problems that were not commonly approached. This gave way to the description of a new PD stage, late-stage PD (LSPD), which is clinically discernible from the advanced-stage one. Therefore, LSPD patients have new and different needs, regarding pharmacological and non pharmacological interventions, including palliative care and multidisciplinary teams. LSPD patients constitute an'orphan population', who traditionally was excluded from previous studies, due to its high disability. With this manuscript, we intend to review specific management challenges of LSPD patients, covering this new concept and its clinical features, how to assess these patients, therapeutic recommendations, as well as discussing ongoing research and future perspectives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.