Evidence map›Paper›PMID 32568110›Full record

ArticleJournal of Parkinson's disease2020

Understanding the Lexicon of Fatigue in Parkinson's Disease.

Sneha Mantri, Emily Klawson, Steven Albert, Karina Nabieva, Madeline Lepore, Stephen Kahl, Margaret Daeschler, Eugenia Mamikonyan, Catherine Kopil, Connie Marras and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
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  9. Article
  10. [Fatigue in chronic physical diseases].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Sneha MantriDepartment of Neurology, Duke University, Durham, NC, USA.
Emily KlawsonDepartment of Behavioral and Community Health Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
Steven AlbertDepartment of Behavioral and Community Health Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
Karina NabievaThe Edmond J Safra Program in Parkinson's disease, Toronto Western Hospital, University of Toronto, Toronto, Ontario, USA.
Madeline LeporeDepartment of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Stephen KahlTuck School of Business, Dartmouth College, Hanover, NH, USA.
Margaret DaeschlerMichael J. Fox Foundation, New York, NY, USA.
Eugenia MamikonyanDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Catherine KopilMichael J. Fox Foundation, New York, NY, USA.
Connie MarrasThe Edmond J Safra Program in Parkinson's disease, Toronto Western Hospital, University of Toronto, Toronto, Ontario, USA.
Lana M ChahineDepartment of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USMichael J. Fox Foundation · USToronto Western Hospital · CADartmouth College · USDuke University · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFatigue in Parkinson's disease (PD) is multifaceted and associated with reduced quality of life. In turn, the language used by people with PD to describe fatigue is variable and poorly understood. We sought to elucidate the lexicon of fatigue using a qualitative grounded theory approach.

objectiveThe objective of this study was to understand how patients with PD describe fatigue.

methodsA pre-study phase of online journaling (Phase 1) provided information regarding topics of importance to patients. Following this, two independent samples of fatigued subjects were studied. Individuals with PD participated in a telephone interview (Phase 2); interview transcripts were analyzed to develop a detailed codebook. To ensure trustworthiness of the findings, an online survey (Phase 3) was administered to individuals with self-reported PD participating in the online study Fox Insight. The survey included the following question: "How do you define fatigue? Please provide your definition in the space below." The codebook developed from Phase 2 was applied to the Phase 3 responses.

resultsFifteen individuals participated in Phase 2 and 413 individuals completed Phase 3. Fatigue was subdivided into three domains: cognitive, emotional, and physical. Nearly all individuals experienced more than one domain of fatigue. The most common themes included tiredness, lack of energy, and negative motivation.

conclusionFatigue in PD is multidimensional. Questionnaires that only assess the physical impact of fatigue may not be adequate to capture the broad range of experiences of fatigue among people with PD.

Indexed as

Diagnostic Self EvaluationAgedAged, 80 and overFatigueFemaleHealth SurveysHumansMaleMiddle AgedParkinson DiseaseQualitative ResearchFatigueParkinson’s diseasequalitative research

Identifiers

PMID32568110
PMCPMC7458521
OpenAlexW3036033141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.