Evidence map›Paper›PMID 32568072›Full record

ArticleeLife2020

A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe

Benjamin W Okaty, Nikita Sturrock, Yasmin Escobedo Lozoya, YoonJeung Chang, Rebecca A Senft, Krissy A Lyon, Olga V Alekseyenko, Susan M Dymecki

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Article
  2. System-level synchronization and subtype-specific modules govern brain-wide serotonin axon innervation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Dorsal raphe nucleus enkephalin peptide modulates behavioral preference.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Serotonin neurons are necessary for tonic sodium intake inhibition.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  16. Optogenetic Stimulation of Novel Tph2-Cre Rats Advances Insight into Serotonin's Role in Locomotion, Reinforcement, and Compulsivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin W Okaty *Department of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0003-1281-2244
Nikita Sturrock *Department of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0002-1635-6760
Yasmin Escobedo LozoyaDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0001-8197-770X
YoonJeung ChangDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0001-9549-8208
Rebecca A SenftDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0003-0081-4170
Krissy A LyonDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0002-4453-8406
Olga V AlekseyenkoDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0003-1645-5133
Susan M DymeckiDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0003-0910-9881

Funding

TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2M
Genomic mechanisms of firing rate homeostasisR01MH116223 · NIMH · HARVARD MEDICAL SCHOOL · PI DYMECKI, SUSAN M. · 2018 to 2022
$3.0M
Developmental gene networks of 5HT neurons in addiction, aggression, and anxietyR01DA034022 · NIDA · HARVARD MEDICAL SCHOOL · PI DYMECKI, SUSAN M. · 2014 to 2018
$3.0M
Mapping serotonergic neuron subtypes protective for seizure-induced neurological and neurobehavioral changesF31NS108406 · NINDS · HARVARD MEDICAL SCHOOL · PI SENFT, REBECCA ALEXIS · 2018 to 2020
$102k
Circuits, serotonergic neurons, and the modulation of behavior: Characterization of a specialized serotonergic neuron subtype responsive to dopamine and central to social behaviorF99NS108515 · NINDS · HARVARD UNIVERSITY · PI LYON, KRISTINE ANNE · 2018 to 2020
$93k
Howard Hughes Medical InstituteNHLBI NIH HHS T32 HL007901NICHD NIH HHS U54 HD090255NIDA NIH HHS R01 DA034022NIMH NIH HHS R01 MH116223NINDS NIH HHS F31 NS108406NINDS NIH HHS F99 NS108515
6 · The paper itself

Abstract

Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the greatest number of

Indexed as

NeuronsTranscriptomeAnimalsDorsal Raphe NucleusFemaleGene Expression ProfilingMaleMiceMice, Inbred C57BLSingle-Cell AnalysisTranscription FactorsFev protein, mouseTranscription Factorsdorsal raphegeneticsgenomicsmouseneuronal diversityneurosciencePet1serotoninserotonin neuronssingle cell RNA-seq

Identifiers

PMID32568072
PMCPMC7308082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.