ArticleeLife2020
Brain states govern the spatio-temporal dynamics of resting-state functional connectivity.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Time-resolved directional organization of brain networks: distinct strength and temporal signatures from neurophysiology to disease.bioRxiv : the preprint server for biology · 2026Article
- Time-Varying Directed Interactions in Functional Brain Networks: Modeling and Validation.ArXiv · 2026Article
- Behavioral, experiential, and physiological signatures of mind blanking.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A brain-state-informed framework for simultaneous extinction of fear and functional magnetic resonance imaging acquisition in rodents.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Generation of surrogate brain maps preserving spatial autocorrelation through random rotation of geometric eigenmodes.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Spectral-switching analysis reveals real-time neuronal network representations of concurrent spontaneous naturalistic behaviors in human brain.bioRxiv : the preprint server for biology · 2024Article
- Article
- Article
- Group ICA of wide-field calcium imaging data reveals the retrosplenial cortex as a major contributor to cortical activity during anesthesia.Frontiers in cellular neuroscience · 2024Article
- Comparing data-driven physiological denoising approaches for resting-state fMRI: implications for the study of aging.Frontiers in neuroscience · 2024Article
- Why is everyone talking about brain state?Trends in neurosciences · 2023Review
- Effects of hypertension and aging on brain function in spontaneously hypertensive rats: a longitudinal resting-state functional magnetic resonance imaging study.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Assessing brain state and anesthesia level with two-photon calcium signals.Scientific reports · 2023Article
- Behavioral Phenotyping of Bbs6 and Bbs8 Knockout Mice Reveals Major Alterations in Communication and Anxiety.International journal of molecular sciences · 2022Article
- Individual slow wave events give rise to macroscopic fMRI signatures and drive the strength of the BOLD signal in human resting-state EEG-fMRI recordings.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Mind blanking is a distinct mental state linked to a recurrent brain profile of globally positive connectivity during ongoing mentation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Functional states shape the spatiotemporal representation of local and cortex-wide neural activity in mouse sensory cortex.Journal of neurophysiology · 2022Article
- Beyond correlation: functional OPTO-MAgnetic Integration Concept (OPTOMAIC) to reveal the brain-wide signature of local neuronal signals-of-interest.Neurophotonics · 2022Article
- Spatial signatures of anesthesia-induced burst-suppression differ between primates and rodents.eLife · 2022Article
- Source localized infraslow neurofeedback training in people with chronic painful knee osteoarthritis: A randomized, double-blind, sham-controlled feasibility clinical trial.Frontiers in neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Previously, using simultaneous resting-state functional magnetic resonance imaging (fMRI) and photometry-based neuronal calcium recordings in the anesthetized rat, we identified blood oxygenation level-dependent (BOLD) responses directly related to slow calcium waves, revealing a cortex-wide and spatially organized correlate of locally recorded neuronal activity (Schwalm et al., 2017). Here, using the same techniques, we investigate two distinct cortical activity states: persistent activity, in which compartmentalized network dynamics were observed; and slow wave activity, dominated by a cortex-wide BOLD component, suggesting a strong functional coupling of inter-cortical activity. During slow wave activity, we find a correlation between the occurring slow wave events and the strength of functional connectivity between different cortical areas. These findings suggest that down-up transitions of neuronal excitability can drive cortex-wide functional connectivity. This study provides further evidence that changes in functional connectivity are dependent on the brain's current state, directly linked to the generation of slow waves.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.