ReviewMicrobiologyOpen2020
Bactericidal and virucidal activity of ethanol and povidone-iodine.
Review in MicrobiologyOpen, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06135844 (Herpes Simplex Virus-1), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Herpes Simplex Virus-1: A Pilot Study Using Hand Sanitizer
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Pooled it
- Sensitivity Evaluation of Enveloped and Non-enveloped Viruses to Ethanol Using Machine Learning: A Systematic Review.Food and environmental virology · 2024Pooled it
- Development of a Three-Dimensional Mucosal Surface Cast of the CaprineVeterinary sciences · 2026Article
- Validation of digital PCR as a complementary tool to MS2 plaque assay for virucidal activity assessment.Frontiers in public health · 2026Article
- Article
- In vitro virucidal activity of chemical compounds against porcine transmissible gastroenteritis virus and porcine respiratory coronavirus.BMC veterinary research · 2025Article
- The Hygienic Significance of Microbiota and Probiotics for Human Wellbeing.Probiotics and antimicrobial proteins · 2025Review
- Spontaneous Cell Detachment from Temperature Gradients: Getting the Method Ready for Antimicrobial Drug Testing at Cell Culture Level.Sensors (Basel, Switzerland) · 2025Article
- Antiviral activity of contact lens care solutions and rub-and-rinse regimen against adenovirus.Optometry and vision science : official publication of the American Academy of Optometry · 2025Article
- In Vitro Differential Virucidal Efficacy of Alcohol-Based Disinfectants Against Human Norovirus and Its Surrogates.Microorganisms · 2025Article
- Povidone-iodine nasal spray (NasodineFrontiers in medicine · 2025Article
- Uncovering the Benefits of Povidone Iodine Compared to Other Therapeutic Agents in Wound Infection Prevention and Healing Outcomes: A Scoping Review.Journal of multidisciplinary healthcare · 2024Article
- Efficacy of a New Alcohol-Free Organic Acid-Based Hand Sanitizer against Foodborne Pathogens.Toxics · 2023Article
- Mouthwash Effects on the Oral Microbiome: Are They Good, Bad, or Balanced?International dental journal · 2023Review
- Virucidal activity of three standard chemical disinfectants against Ebola virus suspended in tripartite soil and whole blood.Scientific reports · 2023Article
- Evaluation of the Inactivation Efficacy of Four Disinfectants for Feline Parvovirus Derived from Giant Panda.Microorganisms · 2023Article
- Cell death and barrier disruption by clinically used iodine concentrations.Life science alliance · 2023Article
- Optimization of the Process of Eliminating Microorganisms Harmful to Human Health and Threatening Objects Isolated from Historical Materials from the Auschwitz-Birkenau State Museum in Poland (A-BSM) Collection with the Use of Ethanol in the Form of Mist.Materials (Basel, Switzerland) · 2023Article
- Inactivation ofPolish journal of microbiology · 2023Article
- Effect of various concentrations of common organic solvents on the growth and proliferation ability ofPeerJ · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethanol and povidone-iodine (PVP-I) are important microbicides that inactivate bacteria and viruses. The present study provides a review of literature data on the concentration-dependent bactericidal and virucidal activity of ethanol and PVP-I in vitro. A systematic search was performed using the meta-database for biomedicine PubMed. Eventually, 74 studies with original data on the reduction of bacterial and viral infectivity using in vitro tests were analyzed. A safe bactericidal effect of ethanol can be expected at concentrations between 60% and 85%, and the exposure times vary between ≤0.5 and ≥5 min. Within an exposure of up to 5 min, 80%-90% ethanol also exerts virucidal/low-level activity, which includes its action against enveloped viruses plus adeno-, noro-, and rotaviruses. For PVP-I, the best bactericidal and virucidal/high-level effect is present at a concentration range of approx. 0.08%-0.9% depending on the free iodine concentration. The maximum exposure times are 5 min for bacteria and 60 min for viruses. The available data may help optimize the significant inactivation of bacteria and viruses in various areas. However, as the conditions in application practice can vary, concrete recommendations for the application can only be derived to a limited extent.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.