ArticleTumori2020
Unknown SARS-CoV-2 pneumonia detected by PET/CT in patients with cancer.
Article in Tumori, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Coronavirus Disease 2019 (COVID-19) in Molecular Imaging: A Systematic Review of Incidental Detection of SARS-CoV-2 Pneumonia on PET Studies.Seminars in nuclear medicine · 2021Pooled it
- Post-COVID-19 lung disease: utility of biochemical and imaging markers in uncovering residual lung inflammation and monitoring anti-inflammatory therapy, a prospective study.European journal of nuclear medicine and molecular imaging · 2025Article
- The effect of COVID-19 on nuclear medicine and radiopharmacy activities: A global survey.Scientific reports · 2023Article
- The value of FDG-PET/CT imaging in the assessment, monitoring, and management of COVID-19.European physical journal plus · 2023Review
- COVID-19 Pneumonia was Incidentally Detected onMolecular imaging and radionuclide therapy · 2022Article
- Molecular imaging as a tool for evaluation of COVID-19 sequelae - A review of literature.World journal of radiology · 2022Review
- [Diagnostics (Basel, Switzerland) · 2022Article
- Evaluation of SARS-CoV-2-Neutralizing Nanobody Using Virus Receptor Binding Domain-Administered Model Mice.Research (Washington, D.C.) · 2022Article
- Oncology and cardiology positron emission tomography/computed tomography faced with COVID-19: A review of available literature data.Frontiers in medicine · 2022Review
- Positron emission tomography in the COVID-19 pandemic era.European journal of nuclear medicine and molecular imaging · 2021Review
- Covid-19 imaging: A narrative review.Annals of medicine and surgery (2012) · 2021Review
- Prevalence of interstitial pneumonia suggestive of COVID-19 atEuropean journal of nuclear medicine and molecular imaging · 2021Observational
- Pulmonary Findings of [Pathogens (Basel, Switzerland) · 2021Article
- Imaging of COVID-19: CT, MRI, and PET.Seminars in nuclear medicine · 2021Review
- A comprehensive review of imaging findings in COVID-19 - status in early 2021.European journal of nuclear medicine and molecular imaging · 2021Review
- Inflammatory response in lungs and extrapulmonary sites detected by [European journal of nuclear medicine and molecular imaging · 2021Article
- 68Ga-DOTANOC PET/CT With Lung Involvement in the Era of COVID-19 Pandemic.Clinical nuclear medicine · 2021Article
- Lung uptake detected byAmerican journal of nuclear medicine and molecular imaging · 2021Article
- Global research trends in COVID-19 with MRI and PET/CT: a scoping review with bibliometric and network analyses.Clinical and translational imaging · 2021Article
- Asymptomatic COVID-19 cancer patients incidentally discovered during F18-FDG PET/CT monitoring.Medicine and pharmacy reports · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn January 2020, the coronavirus disease 2019 (COVID-19) outbreak in Italy necessitated rigorous application of more restrictive safety procedures in the management and treatment of patients with cancer to ensure patient and staff protection. Identification of respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was a challenge during the pandemic owing to a large number of asymptomatic or mildly symptomatic patients.
methodsWe report 5 patients with unknown SARS-CoV-2 infection undergoing positron emission tomography (PET)/computed tomography (CT) with radiopharmaceuticals targeting different tumor processes:
resultsIn all patients, PET/CT showed increased tracer uptake in the lungs corresponding to CT findings of SARS-CoV-2 pneumonia. Quantitative assessment of tracer uptake showed more elevated values for the glucose analogue
conclusionsOur findings suggest that PET/CT is a sensitive modality to hypothesize SARS-CoV-2 pneumonia in patients with cancer, even when asymptomatic. More data are needed to verify the correlation among immune response to SARS-CoV-2 infection, clinical evolution, and PET results. Under the strict safety measures implemented at the PET center, the number of potentially SARS-CoV-2-positive patients undergoing PET/CT was very low (1.6%), and no staff member has been diagnosed with infection as of April 30, 2020.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.