Evidence map›Paper›PMID 32567494›Full record

ReviewJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners2020

Afatinib for the treatment of

R Donald Harvey, Val R Adams, Tyler Beardslee, Patrick Medina

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06759857 (A Randomized, Open, Positives Parallel-controlled, Multicenter Phase III to Evaluate the Efficacy and Safety of FHND9041 Versus Afatinib in First-line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer), which is not on this map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06759857 phase3enrolling by invitationnot on this mapstarted 2021, after this paper: background citation

A Randomized, Open, Positives Parallel-controlled, Multicenter Phase III to Evaluate the Efficacy and Safety of FHND9041 Versus Afatinib in First-line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer

TypeinterventionalSponsorJiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd.Ran2021 to 2025Enrolled350ConditionsNon Small Cell Lung CancerArmsFHND9041, Afatinib
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
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  19. Cancers · 2024
    Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

R Donald HarveyDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, USA.ORCID https://orcid.org/0000-0002-4217-1313
Val R AdamsDepartment of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, USA.
Tyler BeardsleeWinship Cancer Institute of Emory University, Atlanta, USA.
Patrick MedinaCollege of Medicine, Stephenson Cancer Center, University of Oklahoma, Norman, USA.
Emory University · USUniversity of Kentucky · USUniversity of Oklahoma · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors represent the standard of care in patients with

Indexed as

AfatinibAntineoplastic AgentsCarcinoma, Non-Small-Cell LungErbB ReceptorsGefitinibHumansLung NeoplasmsMutationProgression-Free SurvivalProtein Kinase InhibitorsAfatinibAntineoplastic AgentsEGFR protein, humanErbB ReceptorsGefitinibProtein Kinase InhibitorsAfatinibEGFR mutationnon-small cell lung cancertyrosine kinase inhibitor

Identifiers

PMID32567494
PMCPMC7448811
OpenAlexW3036183865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.