Evidence map›Paper›PMID 32567427›Full record

ArticleThe Journal of international medical research2020

Feasibility of using calibrated cone-beam computed tomography scans to validate the heart dose in left breast post-mastectomy radiotherapy.

Bin Tang, Jiabao Ma, Jinghui Xu, Jie Li, Shengwei Kang, Pei Wang, Fan Wu, Lucia Clara Orlandini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Assessment of dosimetric impact of interfractional 6D setup error in tongue cancer treated with IMRT and VMAT using daily kV-CBCT.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bin TangKey Laboratory of Radiation Physics, Institute of Nuclear Science and Technology, Sichuan University, No. 24, South Section 1, Yihuar, Chengdu, 610065, China.
Jiabao MaDepartment of Radiation Oncology, Sichuan Cancer Hospital & Research Institute, No. 55, the 4th Section, Renmin South Road, Chengdu, 610041, China.
Jinghui XuDepartment of Radiation Oncology, Sichuan Cancer Hospital & Research Institute, No. 55, the 4th Section, Renmin South Road, Chengdu, 610041, China.
Jie LiDepartment of Radiation Oncology, Sichuan Cancer Hospital & Research Institute, No. 55, the 4th Section, Renmin South Road, Chengdu, 610041, China.ORCID https://orcid.org/0000-0001-7163-3778
Shengwei KangKey Laboratory of Radiation Physics, Institute of Nuclear Science and Technology, Sichuan University, No. 24, South Section 1, Yihuar, Chengdu, 610065, China.ORCID https://orcid.org/0000-0001-9281-9889
Pei WangDepartment of Radiation Oncology, Sichuan Cancer Hospital & Research Institute, No. 55, the 4th Section, Renmin South Road, Chengdu, 610041, China.ORCID https://orcid.org/0000-0002-0252-3708
Fan WuDepartment of Radiation Oncology, Sichuan Cancer Hospital & Research Institute, No. 55, the 4th Section, Renmin South Road, Chengdu, 610041, China.
Lucia Clara OrlandiniDepartment of Radiation Oncology, Sichuan Cancer Hospital & Research Institute, No. 55, the 4th Section, Renmin South Road, Chengdu, 610041, China.ORCID https://orcid.org/0000-0002-7033-9689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn post-mastectomy radiotherapy, high-conformal techniques are a valid method for determining the dose distribution around a target. However, the proximity of critical structures is a reason for concern. This study aims to evaluate the feasibility of using calibrated cone-beam computed tomography (CBCT) scans as a valid tool for a timely heart dose evaluation.

methodsA retrospective analysis was conducted on 170 retrospective CBCT scans of 17 patients who underwent high-conformal post-mastectomy irradiation. The delivered doses that were calculated using personalized calibrated CBCT were compared with the doses planned, using the dose-volume histogram dosimetric parameters.

resultsThe heart volume that was evaluated using CBCT presented a mean increase of 6%; this discrepancy impacted the heart dose in 4 of 17 patients, with an absolute increase of V25 Gy (range, 2.5%-7.6%) and an increase in the mean dose (range, 1.1-3.4 Gy). The dose for the target, ipsilateral lung, and contralateral breast remained unchanged.

conclusionUsing CBCT to monitor the dose that is delivered to the heart is feasible, allowing for a timely shift to an adaptive plan if clinically necessary.

Indexed as

BreastBreast NeoplasmsCalibrationChinaCone-Beam Computed TomographyFeasibility StudiesFemaleHeartHumansMastectomyMiddle AgedRadiometryRadiotherapyRadiotherapy DosageRetrospective Studiesadaptive planBreastcone-beam computed tomographyheart doselungpost-mastectomy irradiationradiotherapy

Identifiers

PMID32567427
PMCPMC7309397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.