Evidence map›Paper›PMID 32567248›Full record

ArticleMicrobial biotechnology2020

Are synthetic biology standards applicable in everyday research practice?

Huseyin Tas, Adam Amara, Miguel E Cueva, Nadine Bongaerts, Alicia Calvo-Villamañán, Samir Hamadache, Konstantinos Vavitsas

Abstract read
In one paragraph

Article in Microbial biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huseyin TasSystems and Synthetic Biology Program, Spanish National Center for Biotechnology (CNB-CSIC), Madrid, Spain.ORCID 0000-0003-4804-2237
Adam AmaraManchester Institute of Biotechnology, The University of Manchester, Manchester, UK.ORCID 0000-0003-0489-0533
Miguel E CuevaSynthSys, CSEC and School of Biological Sciences, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-4921-7898
Nadine BongaertsCenter for Research and Interdisciplinarity (CRI), Université de Paris, INSERM U1284, Paris, France.ORCID 0000-0002-6517-4744
Alicia Calvo-VillamañánSynthetic Biology Lab, Institut Pasteur, Paris, France.ORCID 0000-0001-7033-2834
Samir HamadacheDepartment of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Konstantinos VavitsasDepartment of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, Athens, 15784, Greece.ORCID 0000-0002-6828-1000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The issue of standardization in synthetic biology is a recurring one. As a discipline that incorporates engineering principles into biological designs, synthetic biology needs effective ways to communicate results and allow different researchers (both academic and industrial) to build upon previous results and improve on existing designs. An aspect that is left out of the discussions, especially when they happen at the level of academic and industrial consortia or policymaking, is whether or not standards are applicable or even useful in everyday research practice. In this caucus article, we examine this particular issue with the hope of including it in the standardization discussions agenda and provide insights into a topic that synthetic biology researchers experience daily.

Indexed as

Synthetic BiologyReference Standards

Identifiers

PMID32567248
PMCPMC7415368

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.