Evidence map›Paper›PMID 32567008›Full record

ArticleAnnals of nuclear medicine2020

Preclinical PET imaging study of lung cancer with

Qiang Wang, Dongli Song, Xiaowei Ma, Xiaodong Wu, Lei Jiang

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of nuclear medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Preclinical Theranostic Profiling of [Molecules (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Editorial:Frontiers in medicine · 2023
    Article
  6. Recent Advances in Cancer Imaging withNuclear medicine and molecular imaging · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qiang Wang *Department of Nuclear Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, 507 Zhengmin Road, Shanghai, 200433, China.
Dongli Song *Institute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Xiaowei MaMolecular Imaging Program At Stanford, Department of Radiology and Bio-X Program, Canary Center At Stanford for Cancer Early Detection, Stanford University, Stanford, CA, 94305-5484, USA.
Xiaodong WuDepartment of Nuclear Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, 507 Zhengmin Road, Shanghai, 200433, China.
Lei JiangDepartment of Nuclear Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, 507 Zhengmin Road, Shanghai, 200433, China. leijiang1031@163.com.ORCID http://orcid.org/0000-0002-9479-132X

Funding

Major Grant of Research and Development Program of Hunan Province of China 2019SK2252National Natural Science Foundation of China 81571703National Natural Science Foundation of China 81971645Outstanding Young Talents Program of Shanghai Municipal Commission of Health and Family Planning 2017YQ027
6 · The paper itself

Abstract

objectiveHuman copper transporter 1 (CTR1) has been proven to be overexpressed in many types of cancer cells, and copper (II)-64 chloride (

methodsThe expression of CTR1 in a series of lung cancer cell lines was identified by quantitative real-time polymerase chain reaction (Q-PCR), western blot, enzyme-linked immunosorbnent assay (ELISA), and immunofluorescent staining. Then in vitro cell uptake assay of

resultsThe CTR1 expression in multiple human lung cancer cells was identified and confirmed, and H1299 cell lines with high CTR1 expression, H460 with moderate CTR1, and H1703 with low CTR1 were selected for further experiments. In vitro cellular uptake assay displayed that the

conclusionsThe expression of CTR1 in human lung cancer xenograft model could be successfully visualized by

Indexed as

CopperCopper RadioisotopesPositron-Emission TomographyAnimalsCell Line, TumorCell Transformation, NeoplasticCopper Transporter 1FemaleGene Expression Regulation, NeoplasticHumansLung NeoplasmsMiceCopperCopper-64Copper RadioisotopesCopper Transporter 1cupric chlorideSLC31A1 protein, human64CuCl2Human copper transporter 1 (CTR1)Lung cancerPET

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.