Evidence map›Paper›PMID 32567007›Full record

ArticleJournal of molecular neuroscience : MN2021

Cronobacter sakazakii Infection in Early Postnatal Rats Impaired Contextual-Associated Learning: a Putative Role of C5a-Mediated NF-κβ and ASK1 Pathways.

Ponnusamy Vinay, Christopher Karen, Krishnaswamy Balamurugan, Koilmani Emmanuvel Rajan

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Roles and mechanisms ofVirulence · 2025
    Article
  4. Sepsis-Induced Brain Dysfunction: Pathogenesis, Diagnosis, and Treatment.Oxidative medicine and cellular longevity · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ponnusamy VinayBehavioural Neuroscience Laboratory, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, 620024, India.
Christopher KarenBehavioural Neuroscience Laboratory, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, 620024, India.
Krishnaswamy BalamuruganDepartment of Biotechnology, Alagappa University, Karaikudi, 630003, India.
Koilmani Emmanuvel RajanBehavioural Neuroscience Laboratory, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, 620024, India. emmanuvel1972@yahoo.com.ORCID http://orcid.org/0000-0003-2804-8594
Bharathidasan University · INAlagappa University · IN

Funding

Department of Biotechnology , Ministry of Science and Technology BT/PR17367/MED/122/44/2016
6 · The paper itself

Abstract

This study was designed to test whether the Cronobacter sakazakii infection-impaired contextual learning and memory are mediated by the activation of the complement system; subsequent activation of inflammatory signals leads to alternations in serotonin transporter (SERT). To test this, rat pups (postnatal day, PND 15) were treated with either C. sakazakii (10

Indexed as

Complement ActivationADAMTS1 ProteinAnimalsAnimals, SucklingAssociation LearningCerebral CortexComplement C5aCronobacter sakazakiiEnterobacteriaceae InfectionsEscherichia coli InfectionsGene Expression RegulationInflammationInterferon-alphaInterleukin-6Janus KinasesLearning DisabilitiesADAMTS1 ProteinAdamts1 protein, ratAkt3 protein, ratComplement C5aIl6 protein, ratInterferon-alphaInterleukin-6Janus KinasesMAP Kinase Kinase Kinase 1MAP Kinase Kinase Kinase 5Nerve Tissue ProteinsNF-kappa BProto-Oncogene Proteins c-aktSerotoninSerotonin Plasma Membrane Transport ProteinsSlc6a4 protein, ratADAMTSContextual-associated learningCronobacter sakazakiiIL-6NF-κBSepsisSERT

Identifiers

PMID32567007
OpenAlexW3036040122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.