Evidence map›Paper›PMID 32566687›Full record

ArticleJournal of immunology research2020

Poly(vinyl alcohol boric acid)-Diclofenac Sodium Salt Drug Delivery Systems: Experimental and Theoretical Studies.

Daniela Ailincai, Alexandra Maria Dorobanțu, Bogdan Dima, Ștefan Andrei Irimiciuc, Cristian Lupașcu, Maricel Agop, Orzan Olguta

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Daniela AilincaiPetru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, Iasi, Romania.
Alexandra Maria DorobanțuElias Emergency University Hospital, Dermatology Clinic, Bucharest, No. 17 Marasti Bvd., 011461 Bucharest, Romania.ORCID https://orcid.org/0000-0002-7752-7930
Bogdan DimaElias Emergency University Hospital, Dermatology Clinic, Bucharest, No. 17 Marasti Bvd., 011461 Bucharest, Romania.
Ștefan Andrei IrimiciucNational Institute for Laser, Plasma & Radiation Physics, Magurele, Romania.
Cristian LupașcuGrigore T Popa University of Medicine and Pharmacy Iasi, St. Spiridon University Hospital, I Tanasescu VI Butureanu Surgery Clinic 1, Iasi, Romania.ORCID https://orcid.org/0000-0003-1522-5766
Maricel Agop"Gheorghe Asachi" Techical University of Iasi, Department of Physics, D. Mangeron Bvd. No. 73, 700050 Iasi, Romania.ORCID https://orcid.org/0000-0003-2293-5803
Orzan OlgutaCarol Davila University of Medicine and Pharmacy, Elias Emergency University Hospital, Dermatology Clinic, Bucharest, No. 17 Marasti Bvd., 011461 Bucharest, Romania.
Clinical Emergency Hospital Bucharest · ROAcademia Oamenilor de Știință din România · ROCarol Davila University of Medicine and Pharmacy · ROGrigore T. Popa University of Medicine and Pharmacy · ROInstitutul de Chimie Macromoleculară Petru PoniNational Institute for Laser Plasma and Radiation Physics · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of the paper was to simulate the drug release by a multifractal theoretical model, as a valuable method to assess the drug release mechanism. To do this, drug delivery films were prepared by mixing poly(vinyl alcohol boric acid) (PVAB) and diclofenac (DCF) sodium salt drug in different mass ratios from 90/10 to 70/30, in order to obtain drug delivery systems with different releasing rates. The different drug content of the three systems was confirmed by energy-dispersive spectroscopy (EDAX) analysis, and the encapsulation particularities were investigated by scanning electron microscopy (SEM), atomic force microscopy (AFM), and polarized optical microscopy (POM) techniques. The ability of the PVAB matrix to anchor the DCF was assessed by Fourier transform infrared (FTIR) spectroscopy. The

Indexed as

Drug Delivery SystemsAlgorithmsBoric AcidsCyclooxygenase InhibitorsDiclofenacDrug CarriersDrug LiberationKineticsMicroscopy, Atomic ForceModels, TheoreticalPolyvinyl AlcoholSpectroscopy, Fourier Transform Infraredboric acidBoric AcidsCyclooxygenase InhibitorsDiclofenacDrug CarriersPolyvinyl Alcohol

Identifiers

PMID32566687
PMCPMC7281821
OpenAlexW3032240432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.