Evidence map›Paper›PMID 32566555›Full record

ArticleAnnals of translational medicine2020

Breastfeeding of infants born to mothers with COVID-19: a rapid review.

Nan Yang, Siyi Che, Jingyi Zhang, Xia Wang, Yuyi Tang, Jianjian Wang, Liping Huang, Chenglin Wang, Hairong Zhang, Muna Baskota and 13 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Breastfeeding during the COVID-19 pandemic.Frontiers in pediatrics · 2023
    Review
  7. Review
  8. Article
  9. Health of the Newborn and Breastfeeding during the COVID-19 Pandemic: A Literature Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Current methods for diagnosis of human coronaviruses: pros and cons.Analytical and bioanalytical chemistry · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 3 countries.

Nan YangEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Siyi CheDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Jingyi ZhangSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Xia WangDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Yuyi TangDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Jianjian WangSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Liping HuangDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Chenglin WangDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Hairong ZhangEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Muna BaskotaDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Yanfang MaEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
Qi ZhouThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Xufei LuoSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Shu YangCollege of Medical Information Engineering, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Xixi FengSchool of Public Health, Chengdu Medical College, Chengdu 610500, China.
Weiguo LiDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Toshio FukuokaEmergency and Critical Care Center, Department of General Medicine, Department of Research and Medical Education at Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
Hyeong Sik AhnDepartment of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
Myeong Soo LeeKorea Institute of Oriental Medicine, Daejeon, Korea.
Zhengxiu LuoDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Enmei LiuDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Yaolong ChenEvidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China.
COVID-19 Evidence and Recommendations Working Group
China International Science and Technology Cooperation · CNLanzhou University · CNChengdu Medical College · CNChengdu University of Traditional Chinese Medicine · CNKorea University · KRKurashiki Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExisting recommendations on whether mothers with COVID-19 should continue breastfeeding are still conflicting. We aimed to conduct a rapid review of mother-to-child transmission of COVID-19 during breastfeeding.

methodsWe systematically searched Medline, Embase, Web of Science, Cochrane Library, China Biology Medicine disc, China National Knowledge Infrastructure, Wanfang, and preprint articles up to March 2020. We included studies relevant to transmission through milk and respiratory droplets during breastfeeding of mothers with COVID-19, SARS, MERS and influenza. Two reviewers independently screened studies for eligibility, extracted data, assessed risk of bias and used GRADE to assess certainty of evidence.

resultsA total of 4,481 records were identified in our literature search. Six studies (five case reports and one case series) involving 58 mothers (16 mothers with COVID-19, 42 mothers with influenza) and their infants proved eligible. Five case reports showed that the viral nucleic acid tests for all thirteen collected samples of breast milk from mothers with COVID-19 were negative. A case series of 42 influenza infected postpartum mothers taking precautions (hand hygiene and wearing masks) before breastfeeding showed that no neonates were infected with influenza during one-month of follow-up.

conclusionsThe current evidence indicates that SARS-CoV-2 viral nucleic acid has not been detected in breast milk. The benefits of breastfeeding may outweigh the risk of SARS-CoV-2 infection in infants. Mothers with COVID-19 should take appropriate precautions to reduce the risk of transmission via droplets and close contact during breastfeeding.

Indexed as

BreastfeedingCOVID-19infantmother-to-child transmissionrapid review

Identifiers

PMID32566555
PMCPMC7290644
OpenAlexW3029938609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.