Evidence map›Paper›PMID 32566490›Full record

ArticleMethodsX2020

Dimensional distribution control of elongate mineral particles for their use in biological assays.

Ruggero Vigliaturo, Jessica K Choi, Ileana Pérez-Rodríguez, Reto Gieré

Open access · goldAbstract read
In one paragraph

Article in MethodsX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Asbestos and Other Hazardous Fibrous Minerals: Potential Exposure Pathways and Associated Health Risks.International journal of environmental research and public health · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ruggero VigliaturoDepartment of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA, USA.
Jessica K ChoiDepartment of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA, USA.
Ileana Pérez-RodríguezDepartment of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA, USA.
Reto GieréDepartment of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · US

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Trevor M Penning · 2006 to 2026
$35.3M
Environmental Science Project 3 - Social Determinants of Risk and Attitudes AboutP42ES023720 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI BLAIR, IAN ALEXANDER · 2014 to 2018
$11.3M
NIEHS NIH HHS P30 ES013508NIEHS NIH HHS P42 ES023720
6 · The paper itself

Abstract

The aim of the present method is to reduce the dimensional variability of asbestos, elongate mineral particles, and other asbestiform minerals for use in biological assays. Here, the pristine mineral sample is filtered through two nylon meshes of different sizes to obtain a narrower dimensional distribution following a power law. Furthermore, we show that anoxic preparation, autoclaving and storage of the mineral prior to addition into biological cultures did not affect the mineral's chemical properties. This approach avoids the use of highly reactive chemicals modifying mineralogical characteristics and surface properties, which can affect to a major extent mineral toxicity as well as interactions between minerals and biological matter or biofluids. The method can be combined with additional selective approaches to further refine the dimensional range of the minerals. The advantages of this protocol over previous methods are: •Exclusive use of distilled water and 2-propanol, thus eliminating chemicals that can modify bulk or surface properties of the studied minerals.•Successful sterilization of the resulting mineral particles for use in biological assays without compromising mineralogical characteristics.•Applicability of this method across various types of asbestos, elongate mineral particles and, potentially, other hazardous minerals.

Indexed as

AsbestosAutoclaveChrysotileElectron microscopySelective filtrationTremolite-actinolite

Identifiers

PMID32566490
PMCPMC7298544
OpenAlexW3032555284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.