Evidence map›Paper›PMID 32566474›Full record

ArticleBiomedical spectroscopy and imaging2019

Cancer detection in excised breast tumors using terahertz imaging and spectroscopy.

Magda El-Shenawee, Nagma Vohra, Tyler Bowman, Keith Bailey

Abstract read
In one paragraph

Article in Biomedical spectroscopy and imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Terahertz radiation and the skin: a review.Journal of biomedical optics · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Magda El-ShenaweeDepartment of Electrical Engineering, University of Arkansas, Fayetteville, USA.
Nagma VohraDepartment of Electrical Engineering, University of Arkansas, Fayetteville, USA.
Tyler BowmanDepartment of Electrical Engineering, University of Arkansas, Fayetteville, USA.
Keith BaileyOklahoma Animal Disease Diagnostic Laboratory, Oklahoma State University, Stillwater, Oklahoma, USA.

Funding

Research Resource for Human Organs and Tissues (U42)U42OD011158 · OD · NATIONAL DISEASE RESEARCH INTERCHANGE · PI BELL, THOMAS J · 2012 to 2025
$25.0M
Terahertz Imaging for Margin Assessment of Three Dimensional Breast Cancer TumorsR15CA208798 · NCI · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI EL-SHENAWEE, MAGDA · 2017 to 2021
$849k
NCI NIH HHS R15 CA208798NIH HHS U42 OD011158
6 · The paper itself

Abstract

Terahertz imaging and spectroscopy has demonstrated a potential for differentiating tissue types of excised breast cancer tumors. Pulsed terahertz technology provides a broadband frequency range from 0.1 THz to 4 THz for detecting cancerous tissue. Tumor tissue types of interest include cancer typically manifested as infiltrating ductal or lobular carcinomas, fibro-glandular (healthy connective tissues) and fat. In this work, images of breast tumors excised from human and animal models are reviewed. In addition to alternate fresh tissues, breast cancer tissue phantoms are developed to further evaluate terahertz imaging and the potential use of contrast agents. Terahertz results are successfully validated with pathology images, showing strong differentiation between cancerous and healthy tissues for all freshly excised tissues and types. The advantages, challenges and limitations of THz imaging of breast cancer are discussed.

Indexed as

Breast cancerlumpectomymargin assessmentterahertz imagingterahertz spectroscopy

Identifiers

PMID32566474
PMCPMC7304303

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.