Evidence map›Paper›PMID 32566334›Full record

ArticleCase reports in neurological medicine2020

Anti-NMDAR-Positive Small-Cell Lung Cancer Paraneoplastic Limbic Encephalitis: A Case Report and Literature Review.

Raman Sohal, Steven H Adams, Vishal Phogat, Abha Harish, Carlos Ynigo D Lopez, Michael P A Williams, Kamal K Khurana, Basel Abuzuaiter, Nia Jagroop, Bhavya Narapureddy

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in neurological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Raman SohalDepartment of Medicine, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.ORCID https://orcid.org/0000-0001-6792-4943
Steven H AdamsDepartment of Pathology, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.ORCID https://orcid.org/0000-0001-7274-7590
Vishal PhogatDepartment of Medicine, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Abha HarishDepartment of Medicine, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Carlos Ynigo D LopezDepartment of Neurology, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Michael P A WilliamsDepartment of Pathology, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Kamal K KhuranaDepartment of Pathology, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Basel AbuzuaiterDepartment of Medicine, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Nia JagroopDepartment of Medicine, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
Bhavya NarapureddyDepartment of Neurology, SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USA.
SUNY Upstate Medical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionParaneoplastic limbic encephalitis (PLE) is a rare disease that presents as rapid onset dementia characterized by short-term memory loss (STM), anxiety, and behavioral changes. Anti-NMDAR antibodies are unfrequently reported in PLE associated with small-cell lung cancer (SCLC). Given that PLE can precede the diagnosis of cancer, it is very important that once infectious, metabolic, nutritional, or structural disorders associated with short-term memory loss are ruled out that vigorous effort must be made to rule out underlying malignancy. CASE: We report a rare case of PLE as the presenting symptom of SCLC. A 72-year-old male with history of COPD was brought to the ED by his wife after he was found to have short-term memory loss, including forgetfulness of his wedding anniversary the day before, and anxiety. Neurological exam showed impaired short-term recall on MOCA. CT head showed no evidence of infarct. Lumbar puncture was performed which showed lymphocytic pleocytosis, a nonspecific inflammatory change. CSF panel was negative for HSV,

conclusionThis case highlights the importance of recognizing short-term memory loss as a feature of PLE.

Identifiers

PMID32566334
PMCPMC7288224
OpenAlexW3034160626

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.