Evidence map›Paper›PMID 32566294›Full record

ArticleInternational journal of nephrology2020

Low-Dose Maintenance Intravenous Iron Therapy Can Prevent Anemia in Children with End-Stage Renal Disease Undergoing Chronic Hemodialysis.

Cahyani Gita Ambarsari, Partini Pudjiastuti Trihono, Agustina Kadaristiana, Dedi Rachmadi, Murti Andriastuti, Henny Adriani Puspitasari, Taralan Tambunan, Sudung Oloan Pardede, Irawan Mangunatmadja, Eka Laksmi Hidayati

Open access · goldAbstract read
In one paragraph

Article in International journal of nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Cahyani Gita AmbarsariPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.ORCID https://orcid.org/0000-0003-0387-1031
Partini Pudjiastuti TrihonoPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
Agustina KadaristianaPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
Dedi RachmadiPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Pasteur 38, Bandung 40161, Indonesia.
Murti AndriastutiPediatric Hematology-Oncology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
Henny Adriani PuspitasariPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
Taralan TambunanPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
Sudung Oloan PardedePediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.ORCID https://orcid.org/0000-0002-2751-826X
Irawan MangunatmadjaPediatric Neurology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
Eka Laksmi HidayatiPediatric Nephrology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, URJT Building 5th Floor, Diponegoro 71, Jakarta Pusat 10430, Indonesia.
University of Indonesia · IDDr. Hasan Sadikin General Hospital · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency anemia is common in children with end-stage renal disease (ESRD) on long-term hemodialysis receiving erythropoiesis-stimulating agents. One approach to maintain the iron profile and hemoglobin levels is maintenance therapy with regular low doses of intravenous (IV) iron after initial iron repletion therapy; however, evidence for the benefits of this approach is lacking. This study evaluated the effect of IV iron maintenance therapy on anemia in children on regular hemodialysis. This retrospective cohort study included 41 pediatric ESRD patients with normal hemoglobin and iron status who underwent regular hemodialysis at the Pediatric Dialysis Unit of Cipto Mangunkusumo Hospital, Indonesia, between January 2015 and April 2019. Among these, 21 received IV iron maintenance therapy with two doses of 2 mg/kg of IV iron sucrose every 2 weeks (the treatment group) and 20 did not (the comparison group). Changes in hemoglobin and transferrin saturation were assessed after 6 weeks of observation and compared between the two groups. There was a significant reduction in the mean hemoglobin level compared with the baseline level in the comparison group (21 g/L; 95% CI, 9.3-33 g/L;

Identifiers

PMID32566294
PMCPMC7284959
OpenAlexW3031269924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.