Evidence map›Paper›PMID 32566281›Full record

ArticleJournal of nutrition and metabolism2020

Acute Effect of a Protein Supplement on Targeted Plasma Amino Acid Profile among Healthy Asian Indians: A Randomized Controlled Trial.

Ammu Kurien, Nidhi Sharma, Madhavi Marathe, Nandan Joshi, Sumithra Selvam, Sarita Devi, Sucharita Sambashivaiah

Open access · goldAbstract read
In one paragraph

Article in Journal of nutrition and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ammu KurienDivision of Nutrition, St. John's Research Institute, Bengaluru, India.
Nidhi SharmaDivision of Nutrition, St. John's Research Institute, Bengaluru, India.
Madhavi MaratheHealth Care Nutrition Science & Medical Affairs, Nutricia International Pvt. Ltd., Mumbai, India.
Nandan JoshiHealth Care Nutrition Science & Medical Affairs, Nutricia International Pvt. Ltd., Mumbai, India.
Sumithra SelvamDivision of Epidemiology, Biostatistics and Population Health, St. John's Research Institute, Bengaluru, India.
Sarita DeviDivision of Nutrition, St. John's Research Institute, Bengaluru, India.
Sucharita SambashivaiahDepartment of Physiology, St. John's Medical College, Bengaluru, India.ORCID https://orcid.org/0000-0003-2407-383X
St. John's National Academy of Health Sciences · INSt.John's Medical College Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndians have a poor protein intake in terms of quantity as well as quality because of their predominantly cereal-based diet. However, there is limited information on circulatory amino acid levels in healthy Indians. Herein, we evaluated the acute effect of a protein supplement on the plasma levels of essential amino acids (EAAs) in healthy Indian adults, using targeted EAA analysis.

methodsIn this double-blind, randomized, crossover study, 20 healthy Indian adults were randomized to receive the test protein supplement (treatment arm,

resultsAt baseline, mean plasma levels did not differ significantly between the two arms for any of the EAAs. In the treatment arm, the mean levels of all EAAs increased significantly from baseline to 60 min (

conclusionCompared to placebo, protein supplement increased circulatory amino acid levels in healthy Indians. The observed increase in EAA levels and its role in conjunction with exercise in both healthy and diseased states need to be further evaluated. This is the first dataset exploring targeted EAA profiles and the effect of a protein supplement among healthy Indians. The clinical trial is registered with CTRI/2018/12/016777.

Identifiers

PMID32566281
PMCPMC7285395
OpenAlexW3033924966

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.