ArticleJournal of ophthalmology2020
Endothelial Plaques as Sign of Hyphae Infiltration of Descemet's Membrane in Fungal Keratitis.
Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Reverse endothelial scraping technique for refractory deep infectious keratitis: Novel surgical technique and outcome evaluation.Indian journal of ophthalmology · 2026Article
- Comparison of therapeutic effects between big-bubble deep anterior lamellar keratoplasty and penetrating keratoplasty for medically unresponsive Acanthamoeba keratitis.BMC infectious diseases · 2024Article
- Differentiation of acanthamoeba keratitis from other non-acanthamoeba keratitis: Risk factors and clinical features.PloS one · 2024Article
- Two-step strategy-conjunctival flap covering surgery combined with secondary deep anterior lamellar keratoplasty for the treatment of high-risk fungal keratitis.International journal of ophthalmology · 2023Article
- Unusual presentation of fungal keratitis with endothelial plaque.BMJ case reports · 2022Article
- Clinical application of a shape-preserving rapid corneal donor dehydrater.International journal of ophthalmology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the relationship between corneal endothelial plaques and fungal hyphae infiltration in fungal keratitis.
methodsRetrospective cross-sectional study of 60 fungal keratitis patients who underwent keratoplasty between January 2013 and March 2017. The endothelial plaques were graded as follows: grade 1, 1-3 endothelial plaques; grade 2, 4-8 endothelial plaques; and grade 3, more than 8 endothelial plaques or dense, merging endothelial plaques. The fungal pathogen culture and histopathology of diseased Descemet's membrane were evaluated.
resultsAccording to endothelial plaque grading, 3 patients were grade 1, 29 patients were grade 2, and 28 patients were grade 3. The PK surgery was performed in 57 patients with endothelial plaques of grade 2 and grade 3 and DALK surgery in 3 patients of grade 1. The predominating fungal pathogens were
conclusionsEndothelial plaques are considered as a sign of hyphae infiltrating Descemet's membrane. PK should be performed once plaques are detected in endothelium during the surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.