Evidence map›Paper›PMID 32566174›Full record

ReviewFood science & nutrition2020

Review of the effects of vitexin in oxidative stress-related diseases.

Fatemeh Babaei, Armita Moafizad, Zahra Darvishvand, Mohammadreza Mirzababaei, Hossein Hosseinzadeh, Marjan Nassiri-Asl

Open access · hybridAbstract readReview
In one paragraph

Review in Food science & nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 2 syntheses or guidelines pooled it, 163 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. FermentedPharmaceutical biology · 2026
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Fatemeh BabaeiDepartment of Clinical Biochemistry School of Medicine Student Research Committee Shahid Beheshti University of Medical Sciences Tehran Iran.
Armita MoafizadQazvin University of Medical Sciences Qazvin Iran.
Zahra DarvishvandQazvin University of Medical Sciences Qazvin Iran.
Mohammadreza MirzababaeiDepartment of Clinical Biochemistry School of Medicine Kermanshah University of Medical Sciences Kermanshah Iran.
Hossein HosseinzadehPharmaceutical Research Center Pharmaceutical Technology Institute Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-3483-851X
Marjan Nassiri-AslDepartment of Pharmacology and Neurobiology Research Center School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0003-3701-0758
Qazvin University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRKermanshah University of Medical Sciences · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitexin is an apigenin flavone glycoside found in food and medicinal plants. It has a variety of pharmacological effects, including antioxidant, anti-inflammatory, anticancer, antinociceptive, and neuroprotective effects. This review study summarizes all the protective effects of vitexin as an antioxidant against reactive oxygen species, lipid peroxidation, and other oxidative damages in a variety of oxidative stress-related diseases, including seizure, memory impairment, cerebral ischemia, neurotoxicity, myocardial and respiratory injury, and metabolic dysfunction, with possible molecular and cellular mechanisms. This review describes any activation or inhibition of the signaling pathways that depend on the antioxidant activity of vitexin. More basic research is needed on the antioxidative effects of vitexin in vivo, and carrying out clinical trials for the treatment of oxidative stress-related diseases is also recommended.

Indexed as

antioxidantlipid peroxidationoxidative stressreactive oxygen speciesvitexin

Identifiers

PMID32566174
PMCPMC7300089
OpenAlexW3016956465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.