Evidence map›Paper›PMID 32566091›Full record

ReviewOxidative medicine and cellular longevity2020

Interplay between Oxidative Stress, Inflammation, and Amyloidosis in the Anterior Segment of the Eye; Its Pathological Implications.

Roxanna Perez-Garmendia, Alicia Lopez de Eguileta Rodriguez, Ivan Ramos-Martinez, Nayeli Martínez Zuñiga, Roberto Gonzalez-Salinas, Hugo Quiroz-Mercado, Edgar Zenteno, Eleazar Ramírez Hernández, Luis Fernando Hernández-Zimbrón

Abstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Lebanese Medicinal Plants with Ophthalmic Properties.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Review
  8. Potential New Target for Dry Eye Disease-Oxidative Stress.Antioxidants (Basel, Switzerland) · 2024
    Review
  9. Review
  10. Review
  11. Proteostasis in aging-associated ocular disease.Molecular aspects of medicine · 2022
    Review
  12. Review
  13. Oxidative Stress Implication in Retinal Diseases-A Review.Antioxidants (Basel, Switzerland) · 2022
    Review
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roxanna Perez-GarmendiaResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0002-3449-8965
Alicia Lopez de Eguileta RodriguezResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0001-8648-5077
Ivan Ramos-MartinezResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0002-3575-8722
Nayeli Martínez ZuñigaResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0001-5574-4793
Roberto Gonzalez-SalinasResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0001-6654-5191
Hugo Quiroz-MercadoResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.
Edgar ZentenoBiochemistry Department, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0001-5603-4072
Eleazar Ramírez HernándezResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0002-2813-5359
Luis Fernando Hernández-ZimbrónResearch Department, Asociación para Evitar la Ceguera, IAP, México City 04030, Mexico.ORCID https://orcid.org/0000-0002-5098-367X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are different pathologies associated with amyloidogenic processes caused by the increase of reactive oxygen species (ROS) and the overactivation of inflammatory responses. These alterations are present in different regions of the anterior segment of the eye, and they have been associated with the development and progression of ocular pathologies, such as glaucoma, dry eye syndrome, keratitis, and cataracts among other pathologies.

Indexed as

Oxidative StressAmyloidosisAnimalsAnterior Eye SegmentHumansInflammationReactive Oxygen SpeciesTrabecular MeshworkReactive Oxygen Species

Identifiers

PMID32566091
PMCPMC7291327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.