Evidence map›Paper›PMID 32566048›Full record

ArticlePharmacy practice

Evaluation of risk factors and drug adherence in the occurrence of stroke in patients with atrial fibrillation.

Maya El-Hajj, Roula Ajrouche, Salam Zein, Samar Rachidi, Sanaa Awada, Amal Al-Hajje

Open access · diamondAbstract read
In one paragraph

Article in Pharmacy practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Evaluation of the Effectiveness of the Mobile Application on Adherence of Patients With Arterial Hypertension.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maya El-HajjMPH, PhD. Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy. Lebanese University. Beirut (Lebanon). hajj_maya@hotmail.com.ORCID https://orcid.org/0000-0001-9747-5675
Roula AjrouchePharmD. PhD. Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy. Lebanese University. Beirut (Lebanon). rola_ajrouche@hotmail.com.ORCID https://orcid.org/0000-0001-9549-2498
Salam ZeinPharmD, PhD. Clinical and Epidemiological Research Laboratory, Lebanese University. Beirut (Lebanon). salam.zein@ul.edu.lb.ORCID https://orcid.org/0000-0003-4401-7480
Samar RachidiPharmD, PhD. Clinical and Epidemiological Research Laboratory, Lebanese University. Beirut (Lebanon). samar.rachidi@outlook.com.ORCID https://orcid.org/0000-0003-4781-9526
Sanaa AwadaPharmD, PhD. Clinical and Epidemiological Research Laboratory, Lebanese University. Beirut (Lebanon). sanaa3a@hotmail.com.ORCID https://orcid.org/0000-0001-9482-2483
Amal Al-HajjePharmD, PhD. Clinical and Epidemiological Research Laboratory, Lebanese University. Beirut (Lebanon). amalkeh@hotmail.com.ORCID https://orcid.org/0000-0001-7810-3390
Lebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) patients are at high risk of developing a stroke and anticoagulant medications are generally prescribed to prevent stroke in AF population.

objectiveThis study aims to evaluate stroke risk factors among hospitalized patients with AF and to assess the level of adherence to medications in AF patients and their relation with stroke.

methodsThis is a case-control study conducted between June 1

resultsIn total, 174 cases of AF patients were included with 87 cases and 87 controls. The risk of stroke among AF significantly increased with the presence of a history of hypertension, aOR 16.04 (95%CI, 2.27-113.37; p=0.005), history of coronary heart disease/myocardial infarction, and history of obesity. Anticoagulant medication significantly decreased the risk of stroke among AF patients, aOR 0.27 (95%CI, 0.07-0.98; P=0.047). High adherence to medications was significantly associated with a reduced risk of stroke, aOR 0.04 (95%CI, 0.01-0.23; p<0.001).

conclusionsHaving a history of hypertension is one of the strongest risk factors for stroke among AF patients in Lebanon. While anticoagulant medication use was associated with a reduced risk for stroke, high adherence to medications is critical for stroke prevention. Public health interventions are needed to tackle low-adherence to medication and prevent stroke among AF patients.

Indexed as

AnticoagulantsAtrial FibrillationCase-Control StudiesCoronary DiseaseHypertensionInpatientsLebanonLogistic ModelsMedication AdherenceObesityOdds RatioRisk FactorsStroke

Identifiers

PMID32566048
PMCPMC7290178
OpenAlexW3033576712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.