Evidence map›Paper›PMID 32566030›Full record

ArticleBeilstein journal of organic chemistry2020

Synthesis, antiinflammatory activity, and molecular docking studies of bisphosphonic esters as potential MMP-8 and MMP-9 inhibitors.

Abimelek Cortes-Pacheco, María Adelina Jiménez-Arellanes, Francisco José Palacios-Can, José Antonio Valcarcel-Gamiño, Rodrigo Said Razo-Hernández, María Del Carmen Juárez-Vázquez, Adolfo López-Torres, Oscar Abelardo Ramírez-Marroquín

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Abimelek Cortes-PachecoInstituto de Química Aplicada, Universidad del Papaloapan. Tuxtepec, 68301, Mexico.ORCID https://orcid.org/0000-0003-3982-8203
María Adelina Jiménez-ArellanesUnidad de Investigación Médica (UIM) en Farmacología, UMAE Hospital de Especialidades, Centro Médico Nacional Siglo XXI (CMN-SXXI), Instituto Mexicano del Seguro Social (IMSS). Av. Cuauhtémoc 330, Col. Doctores 06720, Ciudad de México (CdMx), Mexico.ORCID https://orcid.org/0000-0002-9379-5601
Francisco José Palacios-CanCentro de Investigación en Dinámica Celular, Universidad Autónoma del Estado de Morelos Avenida Universidad 1001, Chamilpa, 62210 Cuernavaca, Morelos, Mexico.
José Antonio Valcarcel-GamiñoCentro de Investigación en Dinámica Celular, Universidad Autónoma del Estado de Morelos Avenida Universidad 1001, Chamilpa, 62210 Cuernavaca, Morelos, Mexico.
Rodrigo Said Razo-HernándezCentro de Investigación en Dinámica Celular, Universidad Autónoma del Estado de Morelos Avenida Universidad 1001, Chamilpa, 62210 Cuernavaca, Morelos, Mexico.ORCID https://orcid.org/0000-0002-9716-9376
María Del Carmen Juárez-VázquezUnidad de Investigación Médica (UIM) en Farmacología, UMAE Hospital de Especialidades, Centro Médico Nacional Siglo XXI (CMN-SXXI), Instituto Mexicano del Seguro Social (IMSS). Av. Cuauhtémoc 330, Col. Doctores 06720, Ciudad de México (CdMx), Mexico.
Adolfo López-TorresInstituto de Química Aplicada, Universidad del Papaloapan. Tuxtepec, 68301, Mexico.
Oscar Abelardo Ramírez-MarroquínInstituto de Química Aplicada, Universidad del Papaloapan. Tuxtepec, 68301, Mexico.ORCID https://orcid.org/0000-0003-4354-5468
Mexican Social Security Institute · MXUniversidad Autónoma del Estado de Morelos · MXUniversidad del Papaloapan · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphosphonic acids (or bisphosphonates) have been successfully used in the clinic treatment of bone diseases for over decades. Additionally, the antiinflammatory activity of these compounds has been gaining attention. In our previous work, we synthesized and in vivo evaluated the bisphosphonic esters

Indexed as

inflammationmolecular dockingorganophosphorus compounds

Identifiers

PMID32566030
PMCPMC7296197
OpenAlexW3033592537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.