Evidence map›Paper›PMID 32565959›Full record

ArticleOncology letters2020

Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma.

Wen-Wen Lin, Guan-Yong Ou, Jia-Zhe Lin, San-Jun Yi, Wei-Cheng Yao, Hong-Chao Pan, Wei-Jiang Zhao

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. [Neuregulin 2 is highly expressed in glioma tissues to regulate glial fibrillary acidic protein expressionNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wen-Wen LinCenter for Neuroscience, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Guan-Yong OuCenter for Neuroscience, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Jia-Zhe LinNeurosurgical Department, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
San-Jun YiCenter for Neuroscience, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Wei-Cheng YaoMedical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510120, P.R. China.
Hong-Chao PanCenter for Neuroscience, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Wei-Jiang ZhaoCenter for Neuroscience, Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Shantou University · CNShantou University Medical College · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural cell adhesion molecular L1-like protein (CHL1) is a member of the cell adhesion molecule L1 family and serves an important role in the development and progression of tumors. The cytokine neuregulin 1 (NRG1) has been indicated in the tumorigenesis and promotion of metastasis through the modulation of L1. However, the roles of NRG1 in regulating CHL1 in glioma have not been elucidated. The present study investigated the protein expression levels and roles of CHL1 and the possible correlation between NRG1 and CHL1 protein expression levels in human gliomas, both

Indexed as

cell adhesion molecule L1 likeglioblastomagliomaglioma cell lineneuregulin 1tissue array

Identifiers

PMID32565959
PMCPMC7285836
OpenAlexW3018805559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.