ArticleResearch in autism spectrum disorders2019
The influence of age and ASD on verbal fluency networks.
Article in Research in autism spectrum disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Cognitive and Cerebral Aging Research in Autism: A Systematic Review on an Emerging Topic.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- Atypical antipsychotics for autism spectrum disorder: a network meta-analysis.The Cochrane database of systematic reviews · 2025Pooled it
- Quality of life in adults with autism spectrum disorder: influence of age, sex, and a controlled, randomized mindfulness-based stress reduction pilot intervention.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Trial
- Cognitive Aging Patterns in Autism: Parallel, Accelerated, or Safeguarded?Journal of autism and developmental disorders · 2026Article
- Autistic Trait Level and Reaction Time in Older Adults: The Influence of Sex and Task upon Study Outcome.Autism in adulthood · 2026Article
- Language networks in Autism Spectrum Disorder: A systematic review of connectivity-based fMRI studies.Review journal of autism and developmental disorders · 2025Article
- Autism Spectrum Disorder in adults: an integrative review about strategies for promotion and maintenance of quality of life.Sao Paulo medical journal = Revista paulista de medicina · 2025Review
- Article
- Article
- Editorial for the Special Issue - Language and Reading in Autism: Perspectives from Chinese.Reading and writing · 2023Article
- Sex-related brain connectivity correlates of compensation in adults with autism: insights into female protection.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Effects of age on the hippocampus and verbal memory in adults with autism spectrum disorder: Longitudinal versus cross-sectional findings.Autism research : official journal of the International Society for Autism Research · 2022Article
- Increased Intra-Subject Variability of Neural Activity During Speech Production in People with Autism Spectrum Disorder.Research in autism spectrum disorders · 2022Article
- Intact fluency in autism? A comprehensive approach of verbal fluency task including word imageability and concreteness.Autism research : official journal of the International Society for Autism Research · 2022Article
- Aberrant prefrontal functional connectivity during verbal fluency test is associated with reading comprehension deficits in autism spectrum disorder: An fNIRS study.Frontiers in psychology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe integrity and connectivity of the frontal lobe, which subserves fluency, may be compromised by both ASD and aging. Alternate networks often integrate to help compensate for compromised functions during aging. We used network analyses to study how compensation may overcome age-related compromised in individuals with ASD.
methodParticipants consisted of middle-aged (40-60; n=24) or young (18-25; n=18) right-handed males who have a diagnosis of ASD, and age- and IQ-matched control participants (n=20, 14, respectively). All performed tests of language and executive functioning and a fluency functional MRI task. We first used group individual component analysis (ICA) for each of the 4 groups to determine whether different networks were engaged. An SPM analysis was used to compare activity detected in the network nodes from the ICA analyses.
resultsThe individuals with ASD performed more slowly on two cognitive tasks (Stroop word reading and Trailmaking Part A). The 4 groups engaged different networks during the fluency fMRI task despite equivalent performance. Comparisons of specific regions within these networks indicated younger individuals had greater engagement of the thalamus and supplementary speech area, while older adults engaged the superior temporal gyrus. Individuals with ASD did not disengage from the Default Mode Network during word generation.
conclusionInteractions between diagnosis and aging were not found in this study of young and middle-aged men, but evidence for differential engagement of compensatory networks was observed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.