Evidence map›Paper›PMID 32565782›Full record

ArticleGastroenterology research and practice2020

Dietary Risk Factors Associated with Development of Gastric Cancer in Nepal: A Hospital-Based Case-Control Study.

Sunil Kumar Shah, Dev Ram Sunuwar, Narendra Kumar Chaudhary, Pushpa Rai, Pranil Man Singh Pradhan, Narayan Subedi, Madhu Dixit Devkota

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Sirtuins (SIRTs) As a Novel Target in Gastric Cancer.International journal of molecular sciences · 2022
    Review
  2. Comparison of KRAS gene in circulating tumor DNA levels vs histological grading of colorectal cancer patients through liquid biopsy.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Sunil Kumar ShahPublic Health and Nutrition, Bagmati Welfare Society Nepal, Sarlahi, Nepal.
Dev Ram SunuwarDepartment of Nutrition and Dietetics, Nepal APF Hospital, Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-2544-8296
Narendra Kumar ChaudharyDepartment of Radiology, Nepal Orthopaedic Hospital, Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-7747-4066
Pushpa RaiDepartment of Emergency, Patan Academy of Health Sciences, Lalitpur, Nepal.
Pranil Man Singh PradhanDepartment of Community Medicine, Institute of Medicine, Tribhuwan University, Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-0066-8583
Narayan SubediDepartment of Community Medicine, Institute of Medicine, Tribhuwan University, Kathmandu, Nepal.ORCID https://orcid.org/0000-0002-8752-2244
Madhu Dixit DevkotaUpendra Devkota Memorial National Institute of Neurological and Allied Sciences, Kathmandu, Nepal.
Tribhuvan University · NPAnnapurna Neurological Institute and Allied Sciences · NPNepal Orthopaedic HospitalNepal Red Cross Society · NPPatan Academy of Health Sciences · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesGastric cancer (GC) is one of the most prevalent neoplasms and a leading cause of mortality globally. To our knowledge, its relationship with dietary factors is not adequately studied and understood in the Nepalese context. This study is aimed at exploring the relationship between the possible dietary risk factors responsible for gastric cancer in Nepal.

methodsA hospital-based matched case-control study was conducted in two specialized cancer hospitals in Nepal. A total of 237 participants (79 cases and 158 controls) were included in the study. Patients diagnosed within one year (incidence case) with histologically confirmed gastric cancer were taken as cases, and healthy visitors of gastric and nongastric cancer patients without past and present history or not a suspected information of gastric cancer were included as controls. A face-to-face interview was conducted using a semi-structured food frequency questionnaire. Backward stepwise conditional logistic regression was used to estimate the magnitude of the association between the independent variables and gastric cancer. Results were presented as the crude odds ratio (COR) and adjusted odds ratio (AOR) with 95% confidence intervals (CI). A

resultsIn the adjusted multivariable conditional logistic regression model, an increased risk of gastric cancer was more likely to have higher odds among those respondents who had a high consumption of processed meat (AOR = 3.99, 95% CI: 0.90-17.66), preferences of a high amount of fats/oil (AOR = 4.64, 95% CI: 1.56-13.72), and preferences of high amounts of salts (AOR = 4.18, 95% CI: 1.30-13.44). Conversely, those respondents who consumed higher amounts of fruits (AOR = 0.21, 95% CI: 0.07-0.65) were seen to have lower odds of gastric cancer.

conclusionsOur study found an increased risk of gastric cancer with frequent consumption of red meat, processed meat, high preferences of salt, fats/oil, and condiments. Regular consumption of fruits had a protective effect against gastric cancer. Providing nutrition education, public awareness, and lifestyle modification are primary steps to promote the avoidance of risk factors and change unhealthy dietary habits to prevent gastric cancer in Nepal.

Identifiers

PMID32565782
PMCPMC7290904
OpenAlexW3033019167

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.